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© 1985 IRL Press Ltd.

Microcomputer tools for steady–state enzyme kinetics

David Myers and Graham Palmer

Department of Biochemistry, Rice University P.O. Box 1892, Houston, TX 77251, USA

Three programs useful for the investigation of steady–state kinetics have been developed. Two provide the solution to the steady–state rate equation; the first of these is a straightforward implementation of the rules developed by Chou. The second is a very efficient procedure for evaluating King–Altman diagrams and can be used for quite large mechanisms. The third program provides the numeric solution for a specific mechanism and set of initial conditions; it is well suited to extremely large models.

Received on April 1, 1985; accepted on April 19, 1985

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