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© Oxford University Press

Some features on RNA folding structures of cytochrome c oxidase subunit II and cytochrome P450

Eiji Arakawa 1, Hiroshi Yoshikura 2 and Kenji Yamamoto 1,3,4

1Department of Bacteriology, The National Institute of Health
2Department of Bacteriology, Medical School, The University of Tokyo
3The Bunin Hospital of University of Tokyo, Laboratory of Clinical Microbiology

4To whom correspondence should be addressed

We have defined the folding index of the RNA secondary structure and compared the value of this index obtained from a given RNA molecule with one from the random sequences with the same A, U, G, C ratio. The mRNA of the cytochrome c oxidase subunit II and cytochrome P450 from various species was analyzed. We found that the mRNA of these genes were more folded than the random sequences and the coding regions of these mRNA were as equally folded as the random sequences. This result suggests that the coding region of these mRNA has no more important secondary structure than have the random sequences with the same A, U, G, C ratio.

Received on January 21, 1992; accepted on March 1, 1993

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