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© Oxford University Press

LALNVIEW: a graphical viewer for pairwise sequence alignments

Laurent Duret , Elisabeth Gasteiger and Guy Perrièe 1

Department of Medical Biochemistry, University of Geneva I rue Michel Servet, CH-1211 Geneva 4, Switzerland
1Laboratoire de Biométrie, Génétique et Biologie des Populations, UMR 5558 CNRS. Universite Claude Bernard 43 Bd du 11 Novembre 1918, 69622 Villeurbanne cedex, FranceE-mail: duret{at}dim.hcuge.ch

LALNVIEW is a graphical program for visualising local alignments between two sequences (protein or nucleic acids). Sequences are represented by coloured rectangles to give an overall picture of their similarities. LALNVIEW can display sequence features (exon, intron, active site, domain, propeptide, etc.) along with the alignment. When using LALNVIEW through our Web servers, sequence features are automatically extracted from database annotations (SWISS-PROT, GenBank, EMBL or HOVERGEN) and displayed with the alignment. LALNVIEW is a useful tool for analysing pairwise sequence alignments and for making the link between sequence homology and what is known about the structure or function of sequences. LALNVIEW executables for UNIX, Macintosh and PC computers are freely available from our server (http://expasy.hcuge.ch/sprot/lalnview.html).


Received on April 11, 1996; accepted on July 22, 1996

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