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© Oxford University Press

SEAVIEW and PHYLO_WIN: two graphic tools for sequence alignment and molecular phylogeny

N. Galtier 1, M. Gouy and C. Gautier

CNRS UMR 5558, Biométrie, Génétique et Biologie des Populations. Université Claude Bernard Lyon 1, 43, Boulevard du 11 novembre 1918, 69622 Villeurbanne cedex. France

1To whom correspondence should be addressed. E-mail galtier{at}biomserv.univ-lyonl.fr

SEA VIEW and PHYLO_WIN are two graphic tools for X Windows-Unix computers dedicated to sequence alignment and molecular phylogenetics. SEA VIEW is a sequence alignment editor allowing manual or automatic alignment through an interface with CLUSTALW program. Alignment of large sequences with extensive length differences is made easier by a dot-plot-based routine. The PHYLO_WIN program allows phylogenetic tree building according to most usual methods (neighbor joining with numerous distance estimates, maximum parsimony, maximum likelihood), and a bootstrap analysis with any of them. Reconstructed trees can be drawn, edited, printed, stored, evaluated according to numerous criteria. Taxonomic species groups and sets of conserved regions can be defined by mouse and stored into sequence files, thus avoiding multiple data files. Both tools are entirely mouse driven. On-line help makes them easy to use. They are freely available by anonymous ftp at biom3.univ-lyonl. fr/pub/ mol_phylogeny or http://acnuc.univ-lyonl.fr, or by e-mail to galtier{at}biomserv.univ-lyonl.fr.


Received on July 11, 1996; accepted on August 28, 1996

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Eukaryot CellHome page
R. T. Souza, M. R. M. Santos, F. M. Lima, N. M. El-Sayed, P. J. Myler, J. C. Ruiz, and J. F. da Silveira
New Trypanosoma cruzi Repeated Element That Shows Site Specificity for Insertion
Eukaryot. Cell, July 1, 2007; 6(7): 1228 - 1238.
[Abstract] [Full Text] [PDF]


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Appl. Environ. Microbiol.Home page
P. Narasingarao and M. M. Haggblom
Identification of Anaerobic Selenate-Respiring Bacteria from Aquatic Sediments
Appl. Envir. Microbiol., June 1, 2007; 73(11): 3519 - 3527.
[Abstract] [Full Text] [PDF]


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Int. J. Syst. Evol. Microbiol.Home page
F. Laurent, V. Rodriguez-Nava, L. Noussair, A. Couble, M.-H. Nicolas-Chanoine, and P. Boiron
Nocardia ninae sp. nov., isolated from a bronchial aspirate
Int J Syst Evol Microbiol, April 1, 2007; 57(4): 661 - 665.
[Abstract] [Full Text] [PDF]


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Genome ResHome page
M. Babcock, S. Yatsenko, P. Stankiewicz, J. R. Lupski, and B. E. Morrow
AT-rich repeats associated with chromosome 22q11.2 rearrangement disorders shape human genome architecture on Yq12
Genome Res., April 1, 2007; 17(4): 451 - 460.
[Abstract] [Full Text] [PDF]


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Mol Biol EvolHome page
A. C. Doxey, M. W. F. Yaish, B. A. Moffatt, M. Griffith, and B. J. McConkey
Functional Divergence in the Arabidopsis {beta}-1,3-Glucanase Gene Family Inferred by Phylogenetic Reconstruction of Expression States
Mol. Biol. Evol., April 1, 2007; 24(4): 1045 - 1055.
[Abstract] [Full Text] [PDF]


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J. Clin. Microbiol.Home page
Y. Danin-Poleg, L. A. Cohen, H. Gancz, Y. Y. Broza, H. Goldshmidt, E. Malul, L. Valinsky, L. Lerner, M. Broza, and Y. Kashi
Vibrio cholerae Strain Typing and Phylogeny Study Based on Simple Sequence Repeats
J. Clin. Microbiol., March 1, 2007; 45(3): 736 - 746.
[Abstract] [Full Text] [PDF]


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Mol Biol EvolHome page
B. Brindefalk, J. Viklund, D. Larsson, M. Thollesson, and S. G. E. Andersson
Origin and Evolution of the Mitochondrial Aminoacyl-tRNA Synthetases
Mol. Biol. Evol., March 1, 2007; 24(3): 743 - 756.
[Abstract] [Full Text] [PDF]


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Proc. Natl. Acad. Sci. USAHome page
J. Zluvova, M. Nicolas, A. Berger, I. Negrutiu, and F. Moneger
Premature arrest of the male flower meristem precedes sexual dimorphism in the dioecious plant Silene latifolia
PNAS, December 5, 2006; 103(49): 18854 - 18859.
[Abstract] [Full Text] [PDF]


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Nucleic Acids ResHome page
G. Plotz, C. Welsch, L. Giron-Monzon, P. Friedhoff, M. Albrecht, A. Piiper, R. M. Biondi, T. Lengauer, S. Zeuzem, and J. Raedle
Mutations in the MutS{alpha} interaction interface of MLH1 can abolish DNA mismatch repair
Nucleic Acids Res., December 2, 2006; 34(22): 6574 - 6586.
[Abstract] [Full Text] [PDF]


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J. Clin. Microbiol.Home page
S. M. Turner, R. R. Chaudhuri, Z.-D. Jiang, H. DuPont, C. Gyles, C. W. Penn, M. J. Pallen, and I. R. Henderson
Phylogenetic Comparisons Reveal Multiple Acquisitions of the Toxin Genes by Enterotoxigenic Escherichia coli Strains of Different Evolutionary Lineages
J. Clin. Microbiol., December 1, 2006; 44(12): 4528 - 4536.
[Abstract] [Full Text] [PDF]


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Mol Biol EvolHome page
A. Aouacheria, C. Geourjon, N. Aghajari, V. Navratil, G. Deleage, C. Lethias, and J.-Y. Exposito
Insights into Early Extracellular Matrix Evolution: Spongin Short Chain Collagen-Related Proteins Are Homologous to Basement Membrane Type IV Collagens and Form a Novel Family Widely Distributed in Invertebrates
Mol. Biol. Evol., December 1, 2006; 23(12): 2288 - 2302.
[Abstract] [Full Text] [PDF]


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Genome ResHome page
B. Piegu, R. Guyot, N. Picault, A. Roulin, A. Saniyal, H. Kim, K. Collura, D. S. Brar, S. Jackson, R. A. Wing, et al.
Doubling genome size without polyploidization: Dynamics of retrotransposition-driven genomic expansions in Oryza australiensis, a wild relative of rice
Genome Res., October 1, 2006; 16(10): 1262 - 1269.
[Abstract] [Full Text] [PDF]


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Plant Physiol.Home page
A. Pareek, A. Singh, M. Kumar, H. R. Kushwaha, A. M. Lynn, and S. L. Singla-Pareek
Whole-Genome Analysis of Oryza sativa Reveals Similar Architecture of Two-Component Signaling Machinery with Arabidopsis
Plant Physiology, October 1, 2006; 142(2): 380 - 397.
[Abstract] [Full Text] [PDF]


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J. Virol.Home page
G. Delhon, E. R. Tulman, C. L. Afonso, Z. Lu, J. J. Becnel, B. A. Moser, G. F. Kutish, and D. L. Rock
Genome of invertebrate iridescent virus type 3 (mosquito iridescent virus).
J. Virol., September 1, 2006; 80(17): 8439 - 8449.
[Abstract] [Full Text] [PDF]


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J. Virol.Home page
M.-P. Egloff, H. Malet, A. Putics, M. Heinonen, H. Dutartre, A. Frangeul, A. Gruez, V. Campanacci, C. Cambillau, J. Ziebuhr, et al.
Structural and Functional Basis for ADP-Ribose and Poly(ADP-Ribose) Binding by Viral Macro Domains.
J. Virol., September 1, 2006; 80(17): 8493 - 8502.
[Abstract] [Full Text] [PDF]


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J. Virol.Home page
E. R. Tulman, G. Delhon, C. L. Afonso, Z. Lu, L. Zsak, N. T. Sandybaev, U. Z. Kerembekova, V. L. Zaitsev, G. F. Kutish, and D. L. Rock
Genome of horsepox virus.
J. Virol., September 1, 2006; 80(18): 9244 - 9258.
[Abstract] [Full Text] [PDF]


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J. Lipid Res.Home page
P. A. Wilson, S. D. Gardner, N. M. Lambie, S. A. Commans, and D. J. Crowther
Characterization of the human patatin-like phospholipase family
J. Lipid Res., September 1, 2006; 47(9): 1940 - 1949.
[Abstract] [Full Text] [PDF]


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Mol Biol EvolHome page
F. G. Brunet, H. R. Crollius, M. Paris, J.-M. Aury, P. Gibert, O. Jaillon, V. Laudet, and M. Robinson-Rechavi
Gene Loss and Evolutionary Rates Following Whole-Genome Duplication in Teleost Fishes
Mol. Biol. Evol., September 1, 2006; 23(9): 1808 - 1816.
[Abstract] [Full Text] [PDF]


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Int. J. Syst. Evol. Microbiol.Home page
L. Urios, H. Agogue, F. Lesongeur, E. Stackebrandt, and P. Lebaron
Balneola vulgaris gen. nov., sp. nov., a member of the phylum Bacteroidetes from the north-western Mediterranean Sea.
Int J Syst Evol Microbiol, August 1, 2006; 56(Pt 8): 1883 - 1887.
[Abstract] [Full Text] [PDF]


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Microbiol. Mol. Biol. Rev.Home page
M. K. Ashby and J. Houmard
Cyanobacterial Two-Component Proteins: Structure, Diversity, Distribution, and Evolution
Microbiol. Mol. Biol. Rev., June 1, 2006; 70(2): 472 - 509.
[Abstract] [Full Text] [PDF]


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Mol. Biol. CellHome page
D. Wloga, A. Camba, K. Rogowski, G. Manning, M. Jerka-Dziadosz, and J. Gaertig
Members of the NIMA-related Kinase Family Promote Disassembly of Cilia by Multiple Mechanisms
Mol. Biol. Cell, June 1, 2006; 17(6): 2799 - 2810.
[Abstract] [Full Text] [PDF]


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J. Virol.Home page
C. L. Afonso, E. R. Tulman, G. Delhon, Z. Lu, G. J. Viljoen, D. B. Wallace, G. F. Kutish, and D. L. Rock
Genome of crocodilepox virus.
J. Virol., May 1, 2006; 80(10): 4978 - 4991.
[Abstract] [Full Text] [PDF]


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BioinformaticsHome page
M. Sammeth, T. Griebel, F. Tille, and J. Stoye
Panta rhei (QAlign2): an open graphical environment for sequence analysis
Bioinformatics, April 1, 2006; 22(7): 889 - 890.
[Abstract] [Full Text] [PDF]


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Mol Biol EvolHome page
M. Novinec, D. Kordis, V. Turk, and B. Lenarcic
Diversity and Evolution of the Thyroglobulin Type-1 Domain Superfamily
Mol. Biol. Evol., April 1, 2006; 23(4): 744 - 755.
[Abstract] [Full Text] [PDF]


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Mol Biol EvolHome page
A. Schluter, S. Fourcade, R. Ripp, J. L. Mandel, O. Poch, and A. Pujol
The Evolutionary Origin of Peroxisomes: An ER-Peroxisome Connection
Mol. Biol. Evol., April 1, 2006; 23(4): 838 - 845.
[Abstract] [Full Text] [PDF]


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Plant Physiol.Home page
W. I.L. Tameling, J. H. Vossen, M. Albrecht, T. Lengauer, J. A. Berden, M. A. Haring, B. J.C. Cornelissen, and F. L.W. Takken
Mutations in the NB-ARC Domain of I-2 That Impair ATP Hydrolysis Cause Autoactivation
Plant Physiology, April 1, 2006; 140(4): 1233 - 1245.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
T. A. Fritz, J. Raman, and L. A. Tabak
Dynamic Association between the Catalytic and Lectin Domains of Human UDP-GalNAc:Polypeptide {alpha}-N-Acetylgalactosaminyltransferase-2
J. Biol. Chem., March 31, 2006; 281(13): 8613 - 8619.
[Abstract] [Full Text] [PDF]


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Nucleic Acids ResHome page
J.-P. Pichon, B. Bonnaud, P. Cleuziat, and F. Mallet
Multiplex degenerate PCR coupled with an oligo sorbent array for human endogenous retrovirus expression profiling
Nucleic Acids Res., March 22, 2006; 34(6): e46 - e46.
[Abstract] [Full Text] [PDF]


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Appl. Environ. Microbiol.Home page
S. Eichler, R. Christen, C. Holtje, P. Westphal, J. Botel, I. Brettar, A. Mehling, and M. G. Hofle
Composition and Dynamics of Bacterial Communities of a Drinking Water Supply System as Assessed by RNA- and DNA-Based 16S rRNA Gene Fingerprinting.
Appl. Envir. Microbiol., March 1, 2006; 72(3): 1858 - 1872.
[Abstract] [Full Text] [PDF]


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Appl. Environ. Microbiol.Home page
A.-M. Grenier, G. Duport, S. Pages, G. Condemine, and Y. Rahbe
The Phytopathogen Dickeya dadantii (Erwinia chrysanthemi 3937) Is a Pathogen of the Pea Aphid.
Appl. Envir. Microbiol., March 1, 2006; 72(3): 1956 - 1965.
[Abstract] [Full Text] [PDF]


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Proc. Natl. Acad. Sci. USAHome page
H. Tostivint, L. Joly, I. Lihrmann, C. Parmentier, A. Lebon, M. Morisson, A. Calas, M. Ekker, and H. Vaudry
Comparative genomics provides evidence for close evolutionary relationships between the urotensin II and somatostatin gene families
PNAS, February 14, 2006; 103(7): 2237 - 2242.
[Abstract] [Full Text] [PDF]


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J. Clin. Microbiol.Home page
V. Rodriguez-Nava, A. Couble, G. Devulder, J.-P. Flandrois, P. Boiron, and F. Laurent
Use of PCR-Restriction Enzyme Pattern Analysis and Sequencing Database for hsp65 Gene-Based Identification of Nocardia Species
J. Clin. Microbiol., February 1, 2006; 44(2): 536 - 546.
[Abstract] [Full Text] [PDF]


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Syst BiolHome page
A. G. Collins, P. Schuchert, A. C. Marques, T. Jankowski, M. Medina, and B. Schierwater
Medusozoan Phylogeny and Character Evolution Clarified by New Large and Small Subunit rDNA Data and an Assessment of the Utility of Phylogenetic Mixture Models
Syst Biol, February 1, 2006; 55(1): 97 - 115.
[Abstract] [Full Text] [PDF]


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Nucleic Acids ResHome page
B. Anand, S. K. Verma, and B. Prakash
Structural stabilization of GTP-binding domains in circularly permuted GTPases: implications for RNA binding.
Nucleic Acids Res., January 1, 2006; 34(8): 2196 - 2205.
[Abstract] [Full Text] [PDF]


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J. Clin. Microbiol.Home page
V. Rodriguez-Nava, A. Couble, Z. U. Khan, M. Perouse de Montclos, L. Brasme, C. Villuendas, C. Molinard, P. Boiron, and F. Laurent
Nocardia ignorata, a New Agent of Human Nocardiosis Isolated from Respiratory Specimens in Europe and Soil Samples from Kuwait
J. Clin. Microbiol., December 1, 2005; 43(12): 6167 - 6170.
[Abstract] [Full Text] [PDF]



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