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© Oxford University Press

Regional assignment of genetic markers using a somatic cell hybrid panel: a WWW interactive program available for the pig genome

Claude Chevalet , Jérôme Gouzy 1 and Magali SanCristobal-Gaudy

Laboratoire de Genetique Cellulaire Institut National de la Recherche Agronomique BP 27, 31326 Castanet Tolosan Cedex France
1Laboratoire de Biologie Moleculaire des Relations Plantes Microorganismes, Institut National de la Recherche Agronomique BP 27, 31326 Castanet Tolosan Cedex France

Motivation: Quick and easy gene mapping by the use of a panel of cytogenetically characterized somatic cell hybrids is possible, even if some discordant experimental results arise.

Results: An interactive program is proposed and is made available on a WWW site to users of a somatic cell hybrid panel. Assignments to chromosomes and subchromosomal regions are based on likelihood calculations and Bayes' theorem, and a confidence level is provided. The method is illustrated in the case of the pig genome.

Availability: The program can be accessed free of charge at URL http:/ /www. toulouse. inra.fr/lgc/lgc.html.

Contact: E-mail: chevalet{at}toulouse.inra.fr

Received on July 22, 1996; revised on September 12, 1996; accepted on September 18, 1996

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