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Bioinformatics, Vol 14, 74-80, Copyright © 1998 by Oxford University Press


ARTICLES

Xlandscape: the graphical display of word frequencies in sequences

S Levy, L Compagnoni, EW Myers and GD Stormo
University of Colorado, Boulder 80309-0347, USA.

MOTIVATION: To provide a graphical interface for the generation, display and manipulation of a sequence landscape that will run on all X- windows-based Unix workstations. RESULTS: The sequence landscape approach enables the representation of the frequency of occurrence of all query sequence sub-words within a database. The landscape approach can detect tandem and other repeating word motifs, specific sub-words that are over-represented words in a particular database using Markov probability and the preference for sub-words belonging to either one of two databases. All these features aid in the classification of a query sequence. Given the open-text format for sequences and databases, the Xlandscape tool can be applied to a wide range of problems.
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