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Bioinformatics, Vol 14, 542-543, Copyright © 1998 by Oxford University Press


ARTICLES

EUCLID: automatic classification of proteins in functional classes by their database annotations

J Tamames, C Ouzounis, G Casari, C Sander and A Valencia
Protein Design Group, CNB-CSIC, Campus U. Autonoma, Cantoblanco, E- 28049 Madrid, Spain, 2EMBL-EBI, Cambridge CB10 1SD, UK and 3Lion-AG, Heidelberg, Germany.

SUMMARY: A tool is described for the automatic classification of sequences in functional classes using their database annotations. The Euclid system is based on a simple learning procedure from examples provided by human experts. AVAILABILITY: Euclid is freely available for academics at http://www.gredos.cnb.uam.es/EUCLID, with the corresponding dictionaries for the generation of three, eight and 14 functional classes. Contact: E-mail: valencia@cnb.uam.es SUPPLEMENTARY INFORMATION: The results of the EUCLID classification of different genomes are available at http://www.sander.ebi.ac. uk/genequiz/. A detailed description of the different applications mentioned in the text is available at http://www.gredos.cnb.uam. es/EUCLID/Full_Paper
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