Bioinformatics, Vol 15, 510-520, Copyright © 1999 by Oxford University Press
PG Baker, CA Goble, S Bechhofer, NW Paton, R Stevens and A Brass
MOTIVATION: An ontology of biological terminology provides a model of
biological concepts that can be used to form a semantic framework for many
data storage, retrieval and analysis tasks. Such a semantic framework could
be used to underpin a range of important bioinformatics tasks, such as the
querying of heterogeneous bioinformatics sources or the systematic
annotation of experimental results. RESULTS: This paper provides an
overview of an ontology [the Transparent Access to Multiple Biological
Information Sources (TAMBIS) ontology or TaO] that describes a wide range
of bioinformatics concepts. The present paper describes the mechanisms used
for delivering the ontology and discusses the ontology's design and
organization, which are crucial for maintaining the coherence of a large
collection of concepts and their relationships. AVAILABILITY: The TAMBIS
system, which uses a subset of the TaO described here, is accessible over
the Web via http://img.cs.man.ac.uk/tambis (although in the first instance,
we will use a password mechanism to limit the load on our server). The
complete model is also available on the Web at the above URL.
ARTICLES
An ontology for bioinformatics applications
School of Biological Sciences and Department of Computer Science, University of Manchester, Oxford Road, Manchester M13 9PT, UK. tambis@cs.man.ac.uk
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