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Bioinformatics Vol. 16 no. 11 2000
Pages 1046-1047
© 2000 Oxford University Press


Applications Note

VISTA : visualizing global DNA sequence alignments of arbitrary length

Chris Mayor 1, Michael Brudno 1, Jody R. Schwartz 2, Alexander Poliakov 2, Edward M. Rubin 2, Kelly A. Frazer 2, Lior S. Pachter 3, and Inna Dubchak 1,

1 National Energy Research Scientific Computing Center
2 Genome Sciences Department, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
3 Department of Mathematics University of California at Berkeley, Berkeley, CA 94720, USA

Received on June 1, 2000 ; revised on July 19, 2000 ; accepted on August 2, 2000

Summary: VISTA is a program for visualizing global DNA sequence alignments of arbitrary length. It has a clean output, allowing for easy identification of similarity, and is easily configurable, enabling the visualization of alignments of various lengths at different levels of resolution. It is currently available on the web, thus allowing for easy access by all researchers.

Availability: VISTA server is available on the web at http://www-gsd.lbl.gov/vista. The source code is available upon request.

Contact: vista{at}lbl.gov

To whom correspondence should be addressed.


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J. W. Streb, C. M. Kitchen, I. H. Gelman, and J. M. Miano
Multiple Promoters Direct Expression of Three AKAP12 Isoforms with Distinct Subcellular and Tissue Distribution Profiles
J. Biol. Chem., December 31, 2004; 279(53): 56014 - 56023.
[Abstract] [Full Text] [PDF]


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RNAHome page
D. L. PHILIPPS, J. W. PARK, and B. R. GRAVELEY
A computational and experimental approach toward a priori identification of alternatively spliced exons
RNA, December 1, 2004; 10(12): 1838 - 1844.
[Abstract] [Full Text] [PDF]


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EndocrinologyHome page
C. B. Kaelin, A. W. Xu, X.-Y. Lu, and G. S. Barsh
Transcriptional Regulation of Agouti-Related Protein (Agrp) in Transgenic Mice
Endocrinology, December 1, 2004; 145(12): 5798 - 5806.
[Abstract] [Full Text] [PDF]


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Genome ResHome page
J. P. Noonan, J. Grimwood, J. Danke, J. Schmutz, M. Dickson, C. T. Amemiya, and R. M. Myers
Coelacanth genome sequence reveals the evolutionary history of vertebrate genes
Genome Res., December 1, 2004; 14(12): 2397 - 2405.
[Abstract] [Full Text] [PDF]


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Mol Biol EvolHome page
M. Premzl, J. E. Gready, L. S. Jermiin, T. Simonic, and J. A. Marshall Graves
Evolution of Vertebrate Genes Related to Prion and Shadoo Proteins--Clues from Comparative Genomic Analysis
Mol. Biol. Evol., December 1, 2004; 21(12): 2210 - 2231.
[Abstract] [Full Text] [PDF]


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BloodHome page
V. Valverde-Garduno, B. Guyot, E. Anguita, I. Hamlett, C. Porcher, and P. Vyas
Differences in the chromatin structure and cis-element organization of the human and mouse GATA1 loci: implications for cis-element identification
Blood, November 15, 2004; 104(10): 3106 - 3116.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
S.-H. Im, A. Hueber, S. Monticelli, K.-H. Kang, and A. Rao
Chromatin-level Regulation of the IL10 Gene in T Cells
J. Biol. Chem., November 5, 2004; 279(45): 46818 - 46825.
[Abstract] [Full Text] [PDF]


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DevelopmentHome page
E. Dodou, M. P. Verzi, J. P. Anderson, S.-M. Xu, and B. L. Black
Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development
Development, August 15, 2004; 131(16): 3931 - 3942.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
S. Pal, M. J. Nemeth, D. Bodine, J. L. Miller, J. Svaren, S. L. Thein, P. J. Lowry, and E. H. Bresnick
Neurokinin-B Transcription in Erythroid Cells: DIRECT ACTIVATION BY THE HEMATOPOIETIC TRANSCRIPTION FACTOR GATA-1
J. Biol. Chem., July 23, 2004; 279(30): 31348 - 31356.
[Abstract] [Full Text] [PDF]


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DevelopmentHome page
D. Kurokawa, N. Takasaki, H. Kiyonari, R. Nakayama, C. Kimura-Yoshida, I. Matsuo, and S. Aizawa
Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm
Development, July 15, 2004; 131(14): 3307 - 3317.
[Abstract] [Full Text] [PDF]


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Physiol. GenomicsHome page
C. J. Hatcher, N. Y.S.-G. Diman, M.-S. Kim, D. Pennisi, Y. Song, M. M. Goldstein, T. Mikawa, and C. T. Basson
A role for Tbx5 in proepicardial cell migration during cardiogenesis
Physiol Genomics, July 8, 2004; 18(2): 129 - 140.
[Abstract] [Full Text] [PDF]


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GeneticsHome page
A. Palsson, A. Rouse, R. Riley-Berger, I. Dworkin, and G. Gibson
Nucleotide Variation in the Egfr Locus of Drosophila melanogaster
Genetics, July 1, 2004; 167(3): 1199 - 1212.
[Abstract] [Full Text] [PDF]


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Nucleic Acids ResHome page
K. A. Frazer, L. Pachter, A. Poliakov, E. M. Rubin, and I. Dubchak
VISTA: computational tools for comparative genomics
Nucleic Acids Res., July 1, 2004; 32(suppl_2): W273 - W279.
[Abstract] [Full Text] [PDF]


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Nucleic Acids ResHome page
I. Ovcharenko, M. A. Nobrega, G. G. Loots, and L. Stubbs
ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes
Nucleic Acids Res., July 1, 2004; 32(suppl_2): W280 - W286.
[Abstract] [Full Text] [PDF]


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Genes Dev.Home page
A. Zuniga, O. Michos, F. Spitz, A.-P. G. Haramis, L. Panman, A. Galli, K. Vintersten, C. Klasen, W. Mansfield, S. Kuc, et al.
Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression
Genes & Dev., July 1, 2004; 18(13): 1553 - 1564.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
M. P. Hardy and L. A. J. O'Neill
The Murine Irak2 Gene Encodes Four Alternatively Spliced Isoforms, Two of Which Are Inhibitory
J. Biol. Chem., June 25, 2004; 279(26): 27699 - 27708.
[Abstract] [Full Text] [PDF]


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Genome ResHome page
I. Ovcharenko, D. Boffelli, and G. G. Loots
eShadow: A Tool for Comparing Closely Related Sequences
Genome Res., June 1, 2004; 14(6): 1191 - 1198.
[Abstract] [Full Text] [PDF]


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DevelopmentHome page
B. T. MacDonald, M. Adamska, and M. H. Meisler
Hypomorphic expression of Dkk1 in the doubleridge mouse: dose dependence and compensatory interactions with Lrp6
Development, June 1, 2004; 131(11): 2543 - 2552.
[Abstract] [Full Text] [PDF]


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Genome ResHome page
S. B. Montgomery, T. Astakhova, M. Bilenky, E. Birney, T. Fu, M. Hassel, C. Melsopp, M. Rak, A. G. Robertson, M. Sleumer, et al.
Sockeye: A 3D Environment for Comparative Genomics
Genome Res., May 1, 2004; 14(5): 956 - 962.
[Abstract] [Full Text] [PDF]


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J. Nutr.Home page
Y. Wang, B. Jones Voy, S. Urs, S. Kim, M. Soltani-Bejnood, N. Quigley, Y.-R. Heo, M. Standridge, B. Andersen, M. Dhar, et al.
The Human Fatty Acid Synthase Gene and De Novo Lipogenesis Are Coordinately Regulated in Human Adipose Tissue
J. Nutr., May 1, 2004; 134(5): 1032 - 1038.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
B. Hou, M. Eren, C. A. Painter, J. W. Covington, J. D. Dixon, J. A. Schoenhard, and D. E. Vaughan
Tumor Necrosis Factor {alpha} Activates the Human Plasminogen Activator Inhibitor-1 Gene through a Distal Nuclear Factor {kappa}B Site
J. Biol. Chem., April 30, 2004; 279(18): 18127 - 18136.
[Abstract] [Full Text] [PDF]


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Circ. Res.Home page
T. J. Nelson, S. A. Duncan, and R. P. Misra
Conserved Enhancer in the Serum Response Factor Promoter Controls Expression During Early Coronary Vasculogenesis
Circ. Res., April 30, 2004; 94(8): 1059 - 1066.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
K. L. Abrams, J. Xu, C. Nativelle-Serpentini, S. Dabirshahsahebi, and M. B. Rogers
An Evolutionary and Molecular Analysis of Bmp2 Expression
J. Biol. Chem., April 16, 2004; 279(16): 15916 - 15928.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
B. Sevetson, S. Taylor, and Y. Pan
Cbfa1/RUNX2 Directs Specific Expression of the Sclerosteosis Gene (SOST)
J. Biol. Chem., April 2, 2004; 279(14): 13849 - 13858.
[Abstract] [Full Text] [PDF]


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Genome ResHome page
M. Brudno, A. Poliakov, A. Salamov, G. M. Cooper, A. Sidow, E. M. Rubin, V. Solovyev, S. Batzoglou, and I. Dubchak
Automated Whole-Genome Multiple Alignment of Rat, Mouse, and Human
Genome Res., April 1, 2004; 14(4): 685 - 692.
[Abstract] [Full Text] [PDF]


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Genome ResHome page
I. Ovcharenko, G. G. Loots, R. C. Hardison, W. Miller, and L. Stubbs
zPicture: Dynamic Alignment and Visualization Tool for Analyzing Conservation Profiles
Genome Res., March 1, 2004; 14(3): 472 - 477.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
D. U. Lee, O. Avni, L. Chen, and A. Rao
A Distal Enhancer in the Interferon-{gamma} (IFN-{gamma}) Locus Revealed by Genome Sequence Comparison
J. Biol. Chem., February 6, 2004; 279(6): 4802 - 4810.
[Abstract] [Full Text] [PDF]


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Am. J. Physiol. Cell Physiol.Home page
I. A. Barash, L. Mathew, A. F. Ryan, J. Chen, and R. L. Lieber
Rapid muscle-specific gene expression changes after a single bout of eccentric contractions in the mouse
Am J Physiol Cell Physiol, February 1, 2004; 286(2): C355 - C364.
[Abstract] [Full Text]


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Proc. Natl. Acad. Sci. USAHome page
R. M. Clark, E. Linton, J. Messing, and J. F. Doebley
Inaugural Article: Pattern of diversity in the genomic region near the maize domestication gene tb1
PNAS, January 20, 2004; 101(3): 700 - 707.
[Abstract] [Full Text] [PDF]


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J. Biol. Chem.Home page
P. Castronuevo, M. A. Thornton, L. E. McCarthy, J. Klimas, and B. P. Schick
DNase I Hypersensitivity Patterns of the Serglycin Proteoglycan Gene in Resting and Phorbol 12-Myristate 13-Acetate-stimulated Human Erythroleukemia (HEL), CHRF 288-11, and HL-60 Cells Compared with Neutrophils and Human Umbilical Vein Endothelial Cells
J. Biol. Chem., December 5, 2003; 278(49): 48704 - 48712.
[Abstract] [Full Text] [PDF]



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