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Bioinformatics Vol. 16 no. 12 2000
Pages 1151-1152
© 2000 Oxford University Press

Applications Note

IE-Kb: intron exon knowledge base

Meena K. Sakharkar 1,*, Pandjassarame Kangueane 1, Tong W. Woon 1, Tin W. Tan 1, Prasanna R. Kolatkar 1, Manyuan Long 2 and Sandro J de Souza 3

1 BioInformatics Centre, National University of Singapore, Singapore 119260, Singapore
2 Department of Ecology and Evolution, University of Chicago, Chicago, Illinois, USA
3 Laboratory of Computational Biology, Ludwig Institute for Cancer Research, Sao Paulo Branch, Rua Prof. Antonio Prudente 109, 4 andar, 01509-010 Sao Paulo, Brazil

Received on June 12, 2000 ; revised on July 31, 2000 ; accepted on August 8, 2000

Summary: IE-Kb (Intron Exon-Knowledge base) illustrates the intron–exon dynamics in eukaryotic genes. We have developed three different knowledge sets, namely ‘Non-redundant ExInt’, ‘Non-redundant Pfam-ExInt complement’ and ‘Non-redundant GenBank eukaryotic subdivisional sets’ to understand this phenomenon. Statistical analysis is performed on each knowledge set and the results are made available online. The entries in knowledge sets are ranked based on their intron length, exon length and protein length with relational hyper-links to the corresponding intron phase, intron position, intron sequence, gene definition and parent GenBank entry.

Availability: http://intron.bic.nus.edu.sg/iekb/iekb.html

Contact: meena{at}bic.nus.edu.sg

* To whom correspondence should be addressed.


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Home page
 Nucleic Acids ResHome page
M. Sakharkar, F. Passetti, J. E. de Souza, M. Long, and S. J. de Souza
ExInt: an Exon Intron Database
Nucleic Acids Res., January 1, 2002; 30(1): 191 - 194.
[Abstract] [Full Text] [PDF]


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