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Bioinformatics Vol. 16 no. 12 2000
Pages 1155-1156
© 2000 Oxford University Press


Applications Note

A simple probabilistic scoring method for protein domain identification

János Murvai , Kristian Vlahoviek and Sándor Pongor

Protein Structure and Function Group, International Centre for Genetic Engineering and Biotechnology, Area Science Park, 34012 Trieste, Italy

Received on July 19, 2000 ; revised on August 16, 2000 ; accepted on August 16, 2000

Summary: A simple heuristic scoring method is described for assigning sequences to known domain types based on BLAST search outputs. The scoring is based on the score distribution of the known domain groups determined from a database versus database comparison and is directly applicable to BLAST output processing.

Availability: The scoring system will be incorporated into the server www.icgeb.trieste.it/sbase/

Contact: murvai{at}icgeb.trieste.it; pongor{at}icgeb.trieste.it


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