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Bioinformatics Vol. 16 no. 3 2000
Pages 292-293
© 2000 Oxford University Press

HELM: searching for helix motifs within protein sequences

Angelo M. Facchiano 1

1 CRISCEB, Centro di Ricerca Interdipartimentale di Scienze Computazionali e Biotecnologiche, Seconda Universitàdi Napoli - via Costantinopoli 16, 80138 Napoli, Italyand Dipartimento di Biochimica e Biofisica, Seconda Universitàdi Napoli - via Costantinopoli 16, 80138 Napoli, Italy

Received on August 4, 1999 ; revised on November 5, 1999 ; accepted on November 29, 1999

Summary: HELM is a web tool designed to automate the analysis of protein sequences searching for alpha helix motifs. This analysis can be useful in protein engineering studies, aimed at the identification of regions to be modified in order to obtain more suitable features of local and/or global stability.

Availability: The tool is available to academic and commercial institutions at the URL http://crisceb.area.na.cnr.it/angelo/PROTEIN_TOOLS/HELM/

Contact: angelo{at}crisceb.area.na.cnr.it


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