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Bioinformatics Vol. 16 no. 3 2000
Pages 296-297
© 2000 Oxford University Press

RRTree: Relative-Rate Tests between groups of sequences on a phylogenetic tree

Marc Robinson-Rechavi 1,3,* and Dorothée Huchon 2

1 Department of Zoology, Tel Aviv University, Ramat Aviv 69978, Israel
2 Institut des Sciences de l’Evolution, UniversitéMontpellier 2, 34095 Montpellier, France

Received on June 17, 1999 ; revised on August 27, 1999 ; accepted on October 20, 1999

Summary: RRTree is a user-friendly program for comparing substitution rates between lineages of protein or DNA sequences, relative to an outgroup, through relative rate tests. Genetic diversity is taken into account through use of several sequences, and phylogenetic relations are integrated by topological weighting.

Availability: The ANSI C source code of RRTree, and compiled versions for Macintosh, MS-DOS/Windows, SUN Solaris, and CGI, are freely available at http://pbil.univ-lyon1.fr/software/rrtree.html

Contact: marc.robinson{at}ens-lyon.fr

*To whom correspondence should be addressed.

3Present address: Laboratoire de Biologie Moléculaire et Cellulaire, Ecole Normale Supérieure de Lyon, 6 allée d’Italie, 69364 Lyon cedex 07, France, marc.robinson@ens-lyon.fr


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