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Bioinformatics Vol. 16 no. 4 2000
Pages 400-401
© 2000 Oxford University Press

Detecting hypermutations in viral sequences with an emphasis on G -> A hypermutation

Patrick P. Rose 1 and Bette T. Korber 1

1 Theoretical Biology and Biophysics, Los Alamos National Laboratories, MS K710 Los Alamos, NM 87544, USA

Received on October 25, 1999 ; revised on November 30, 1999 ; accepted on December 7, 1999

Summary: This program compares sequence sets to a reference sequence, tallies G -> A hypermutations, and presents the results in various tables and graphs, which include dinucleotide context, summaries of all observed nucleotide changes, and stop codons introduced by hypermutation.

Availability: www.hiv.lanl.gov/HYPERMUT/hypermut.html

Contact: pxr{at}t10.lanl.govor btk{at}t10.lanl.gov


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