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Bioinformatics Vol. 16 no. 9 2000
Pages 843-844
© 2000 Oxford University Press

Applications Note

ODNBase—a web database for antisense oligonucleotide effectiveness studies

Michael C. Giddings 1, Olga V. Matveeva 1, John F. Atkins 1 and Raymond F. Gesteland 1

1 Department of Human Genetics, University of Utah, SLC, UT 84112, USA

Received on January 1, 2000 ; revised on April 24, 2000 ; accepted on May 1, 2000

Summary: ODNBase is a database of antisense oligodeoxynucleotides targeted to mammalian mRNAs that were reported in the literature. It includes the oligo sequences tested, the measured effectiveness, the RNA that was targeted, the type of measurement assay used, the oligo concentration applied, and the reference for each oligo. It provides a searchable interface by motif content, activity level, applied concentration and RNA name. Oligo lists matching search criteria can be downloaded in a spreadsheet compatible format.

Availability: The database is available at http://antisense.genetics.utah.edu/, by clicking the ‘ODNBase’ link.

Contact: giddings@genetics.utah.edu


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