Bioinformatics Vol. 16 no. 9 2000
Pages 847-849
© 2000 Oxford University Press
Applications Note |
LIAN 3.0: detecting linkage disequilibrium in multilocus data
1 Max-Planck-Institut
für Chemische
Ökologie, Carl-Zeiss-Promenade 10,
D-07745 Jena, Germany
2 Department of Ecology and Evolution,
University of Chicago, 1101 E. 57th St., Chicago, IL 60637, USA
Received on January 11, 2000
; revised on March 13, 2000
; accepted on May 12, 2000
Summary: LIAN is a program to test the null hypothesis of linkage equilibrium for multilocus data. LIAN incorporates both a Monte Carlo method as well as a novel algebraic method to carry out the hypothesis test. The program further returns the genetic diversity of the sample and the pairwise distances between its members.
Availability: LIAN can be accessed at http://soft.ice.mpg.de/lian
Contact: haubold{at}ice.mpg.de
To whom correspondence should be addressed.
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