Skip Navigation

This Article
Right arrow FREE Full Text (Print PDF) Freely available
Right arrow FREE Full Text (Screen PDF)
Right arrow Comments: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Comments are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (45)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Myasnikova, E.
Right arrow Articles by Reinitz, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Myasnikova, E.
Right arrow Articles by Reinitz, J.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Bioinformatics Vol. 17 no. 1 2001
Pages 3-12
© 2001 Oxford University Press

Original Paper

Registration of the expression patterns of Drosophila segmentation genes by two independent methods

Ekaterina Myasnikova 1, Anastassia Samsonova 1, Konstantin Kozlov 1, Maria Samsonova 1 and John Reinitz 2,*

1 Institute of High Performance Computing and Data Bases, 118 Fontanka emb., St Petersburg 198005, Russia
2 Department of Molecular Biology and Biochemistry, Box 1020 Mt Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6574, USA

Received on April 21, 2000 ; revised on August 9, 2000 ; accepted on August 15, 2000

Motivation: To construct an integrated map of Drosophila segmentation gene expression from partial data taken from individual embryos.

Results: Spline and wavelet based registration techniques were developed to register Drosophila segmentation gene expression data. As ground control points for registration we used the locations of extrema on gene expression patterns, represented in 1D. The registration method was characterized by unprecedented high accuracy. A method for constructing the integrated pattern of gene expression at cellular resolution was designed. These patterns were constructed for 9 segmentation genes belonging to gap and pair-rule classes.

Availability: Programs running on SPARC/SunOS 5.0 platform or Alpha/DU 4.0E systems may be obtained from the authors.

Contact: myasnikova{at}fn.csa.ru

* To whom correspondence should be addressed.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Nucleic Acids ResHome page
A. Pisarev, E. Poustelnikova, M. Samsonova, and J. Reinitz
FlyEx, the quantitative atlas on segmentation gene expression at cellular resolution
Nucleic Acids Res., January 1, 2009; 37(suppl_1): D560 - D566.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
D. Papatsenko and M. S. Levine
Dual regulation by the Hunchback gradient in the Drosophila embryo
PNAS, February 26, 2008; 105(8): 2901 - 2906.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
Y. Fomekong-Nanfack, J. A. Kaandorp, and J. Blom
Efficient parameter estimation for spatio-temporal models of pattern formation: case study of Drosophila melanogaster
Bioinformatics, December 15, 2007; 23(24): 3356 - 3363.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. E. Lott, M. Kreitman, A. Palsson, E. Alekseeva, and M. Z. Ludwig
Canalization of segmentation and its evolution in Drosophila
PNAS, June 26, 2007; 104(26): 10926 - 10931.
[Abstract] [Full Text] [PDF]

Home page
 DevelopmentHome page
A. C. Cerny, G. Bucher, R. Schroder, and M. Klingler
Breakdown of abdominal patterning in the Tribolium Kruppel mutant jaws
Development, December 15, 2005; 132(24): 5353 - 5363.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
L. Diambra and L. d. F. Costa
Complex networks approach to gene expression driven phenotype imaging
Bioinformatics, October 15, 2005; 21(20): 3846 - 3851.
[Abstract] [Full Text] [PDF]

Home page
 GeneticsHome page
J. Jaeger, M. Blagov, D. Kosman, K. N. Kozlov, Manu, E. Myasnikova, S. Surkova, C. E. Vanario-Alonso, M. Samsonova, D. H. Sharp, et al.
Dynamical Analysis of Regulatory Interactions in the Gap Gene System of Drosophila melanogaster
Genetics, August 1, 2004; 167(4): 1721 - 1737.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.