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Bioinformatics Vol. 17 no. 12 2001
Pages 1236-1237
© 2001 Oxford University Press


Applications Note

ProPred: prediction of HLA-DR binding sites

Harpreet Singh and G. P. S. Raghava *

Bioinformatics Centre, Institute of Microbial Technology, Sector 39A, Chandigarh-160036, India

Received on April 24, 2001 ; revised on June 21, 2001 ; accepted on June 21, 2001

Summary: ProPred is a graphical web tool for predicting MHC class II binding regions in antigenic protein sequences. The server implement matrix based prediction algorithm, employing amino-acid/position coefficient table deduced from literature. The predicted binders can be visualized either as peaks in graphical interface or as colored residues in HTML interface. This server might be a useful tool in locating the promiscuous binding regions that can bind to several HLA-DR alleles.

Availability: The server is available at http://www.imtech.res.in/raghava/propred/

Contact: raghava{at}imtech.res.in

Supplementary information: http://www.imtech.res.in/raghava/propred/page3.html

* To whom correspondence should be addressed.


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