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Bioinformatics Vol. 17 no. 4 2001
Pages 375-376
© 2001 Oxford University Press

Applications Note

PALI: a database of alignments and phylogeny of homologous protein structures

S. Sujatha , S. Balaji and N. Srinivasan *

Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India

Received on August 11, 2000 ; revised on November 13, 2000 ; accepted on November 20, 2000

Summary: PALI is a database of structure-based sequence alignments and phylogenetic relationships derived on the basis of three-dimensional structures of homologous proteins. This database enables grouping of pairs of homologous protein structures on the basis of their sequence identity calculated from the structure-based alignment and PALI also enables association of a new sequence to a family and automatic generation of a dendrogram combining the query sequence and homologous protein structures.

Availability: PALI can be accessed on the web at: http://pauling.mbu.iisc.ernet.in/~pali

Contact: ns{at}mbu.iisc.ernet.in

* To whom correspondence should be addressed.


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