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Bioinformatics Vol. 17 no. 4 2001
Pages 385-387
© 2001 Oxford University Press

Applications Note

PhyloBLAST: facilitating phylogenetic analysis of BLAST results

Fiona S. L. Brinkman 1, Ivan Wan 2, Robert E. W. Hancock 1, Ann M. Rose 3 and Steven J. Jones 2,*

1 Department of Microbiology and Immunology, University of British Columbia, Vancouver, Canada V6T 1Z3
2 Genome Sequence Centre, BC Cancer Agency, Vancouver, Canada V5Z 4E6
3 Department of Medical Genetics, University of British Columbia, Vancouver, Canada V6H 3N1

Received on September 8, 2000 ; revised on December 11, 2000 ; accepted on December 13, 2000

Summary: PhyloBLAST is an internet-accessed application based on CGI/Perl programming that compares a users protein sequence to a SwissProt/TREMBL database using BLAST2 and then allows phylogenetic analyses to be performed on selected sequences from the BLAST output. Flexible features such as ability to input your own multiple sequence alignment and use PHYLIP program options provide additional web-based phylogenetic analysis functionality beyond the analysis of a BLAST result.

Availability: This program is available from http://www.pathogenomics.bc.ca/phyloBLAST/ and the source code is freely available from the authors.

Contact: info{at}pathogenomics.bc.ca

* To whom correspondence should be addressed.


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