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Bioinformatics Vol. 17 no. 6 2001
Pages 535-540
© 2001 Oxford University Press

TreeGeneBrowser: phylogenetic data mining of gene sequences from public databases

Ingrid B. Jakobsen 1,3, Jennifer A. Saleeba 2, Michael Poidinger 3 and Timothy G. Littlejohn 1,3,*

1 Australian Genomic Information Centre
2 School of Biological Sciences, University of Sydney, NSW 2006, Australia
3 Entigen Corp., Suite 101, Bay 16, Australian Technology Park, Eveleigh, NSW 2134, Australia

Received on December 11, 2000 ; revised on January 29, 2001 ; accepted on February 5, 2001

Motivation: Sequence databases represent an enormous resource of phylogenetic information, but there is a lack of tools for accessing that information in order to assess the amount of evolutionary information in these databases that may be suitable for phylogenetic reconstruction and for identifying areas of the taxonomy that are under-represented for specific gene sequences.

Results: We have developed TreeGeneBrowser which allows inspection and evaluation of gene sequence data for phylogenetic reconstruction. This program improves the efficiency of identification of genes that may be useful for particular phylogenetic studies and identifies taxa and taxonomic branches that are under-represented in sequence databases.

Availability: The software described here is available for download from ftp://ftp.angis.org.au/pub/TreeGeneBrowser.

Contact: tim{at}entigen.com

* To whom correspondence should be addressed.


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