Bioinformatics Vol. 17 no. 8 2001
Pages 740-741
© 2001 Oxford University Press
Applications Note |
Polylink: to support two-point linkage analysis in autotetraploids
1 Department of Electronics, University of
Kent at Canterbury, Canterbury, Kent CT2 7NF, UK
2 Horticulture Research International, East
Malling, West Malling, Kent ME19 6BJ, UK
3 Institute of Mathematics and Statistics,
University of Kent at Canterbury, Canterbury, Kent CT2 7NF, UK
Received on January 23, 2001
; revised on April 5, 2001
; accepted on April 23, 2001
Summary: Polylink runs under Microsoft Windows (95 or later).
It performs various calculations that are useful for investigating
two-point linkage analysis for autopolyploids, based on the random
chromosome pairing model. These include calculation of offspring
phenotypic probabilities as functions of the recombination fraction,
calculation of theoretical standard errors for the maximum
likelihood estimator of
and numerical computation of maximum
likelihood estimates. It also includes simulation facilities.
Availability: Polylink is free and available from Xiangming Xu via email
Contact: xiangming.xu{at}hri.ac.uk
* To whom correspondence should be addressed.
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