Bioinformatics Vol. 17 no. 9 2001
Pages 849-850
© 2001 Oxford University Press
Applications Note |
The HMMTOP transmembrane topology prediction server
1 Institute of Enzymology, BRC, Hungarian
Academy of Sciences, H-1518 Budapest, PO Box 7, Hungary
2 Department of Biological Physics,
Eötvös
Loránd University, H-1117 Budapest,
Pázmány
P.
sétány
1, Hungary
Received on March 7, 2001
; revised on April 27, 2001
; accepted on May 28, 2001
Summary: The HMMTOP transmembrane topology prediction server predicts both the localization of helical transmembrane segments and the topology of transmembrane proteins. Recently, several improvements have been introduced to the original method. Now, the user is allowed to submit additional information about segment localization to enhance the prediction power. This option improves the prediction accuracy as well as helps the interpretation of experimental results, i.e. in epitope insertion experiments.
Availability: HMMTOP 2.0 is freely available to non-commercial users at http://www.enzim.hu/hmmtop. Source code is also available upon request to academic users.
Contact: tusi{at}enzim.hu
* To whom correspondence should be addressed.
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