Skip Navigation

This Article
Right arrow FREE Full Text (Print PDF) Freely available
Right arrow FREE Full Text (Screen PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Huson, D. H.
Right arrow Articles by Myers, E. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Huson, D. H.
Right arrow Articles by Myers, E. W.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Bioinformatics Vol. 17 no. 90001 2001
Pages S132-S139
© 2001 Oxford University Press

Design of a compartmentalized shotgun assembler for the human genome

Daniel H. Huson , Knut Reinert , Saul A. Kravitz , Karin A. Remington , Art L. Delcher , Ian M. Dew , Mike Flanigan , Aaron L. Halpern , Zhongwu Lai , Clark M. Mobarry , Granger G. Sutton and Eugene W. Myers

Informatics Research, Celera Genomics, 45 West Gude Drive, Rockville, 20850, USA

Received on February 5, 2001 ; revised on March 30, 2001 ; accepted on March 30, 2001

Two different strategies for determining the human genome are currently being pursued: one is the "clone-by-clone" approach, employed by the publicly funded project, and the other is the "whole genome shotgun assembler" approach, favored by researchers at Celera Genomics. An interim strategy employed at Celera, called compartmentalized shotgun assembly, makes use of preliminary data produced by both approaches. In this paper we describe the design, implementation and operation of the "compartmentalized shotgun assembler".

Contact: Knut.Reinert{at}celera.com


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Proc. Natl. Acad. Sci. USAHome page
S. M. D. Goldberg, J. Johnson, D. Busam, T. Feldblyum, S. Ferriera, R. Friedman, A. Halpern, H. Khouri, S. A. Kravitz, F. M. Lauro, et al.
A Sanger/pyrosequencing hybrid approach for the generation of high-quality draft assemblies of marine microbial genomes
PNAS, July 25, 2006; 103(30): 11240 - 11245.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
X. Huang, S.-P. Yang, A. T. Chinwalla, L. W. Hillier, P. Minx, E. R. Mardis, and R. K. Wilson
Application of a superword array in genome assembly
Nucleic Acids Res., January 5, 2006; 34(1): 201 - 205.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
E. W. Schmidt, J. T. Nelson, D. A. Rasko, S. Sudek, J. A. Eisen, M. G. Haygood, and J. Ravel
Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patella
PNAS, May 17, 2005; 102(20): 7315 - 7320.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
D. Bartels, S. Kespohl, S. Albaum, T. Druke, A. Goesmann, J. Herold, O. Kaiser, A. Puhler, F. Pfeiffer, G. Raddatz, et al.
BACCardI--a tool for the validation of genomic assemblies, assisting genome finishing and intergenome comparison
Bioinformatics, April 1, 2005; 21(7): 853 - 859.
[Abstract] [Full Text] [PDF]

Home page
 Genome ResHome page
P. Havlak, R. Chen, K. J. Durbin, A. Egan, Y. Ren, X.-Z. Song, G. M. Weinstock, and R. A. Gibbs
The Atlas Genome Assembly System
Genome Res., April 1, 2004; 14(4): 721 - 732.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
S. Istrail, G. G. Sutton, L. Florea, A. L. Halpern, C. M. Mobarry, R. Lippert, B. Walenz, H. Shatkay, I. Dew, J. R. Miller, et al.
Whole-genome shotgun assembly and comparison of human genome assemblies
PNAS, February 17, 2004; 101(7): 1916 - 1921.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.