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Bioinformatics Vol. 17 no. 90001 2001
Pages S279-S287
© 2001 Oxford University Press

Separation of samples into their constituents using gene expression data

D. Venet 1,2, F. Pecasse 1, C. Maenhaut 1 and H. Bersini 2

1 I.R.I.B.H.N., Campus Hopital Erasme, Route de Lennik 808 Bat C-CP602, Brussels, B-1070, Belgium
2 I.R.I.D.I.A., UniversitéLibre de Bruxelles, 50, Av. F. Roosevelt, CP 194/6, Brussels, B-1050, Belgium

Received on February 5, 2001 ; revised on April 2, 2001 ; accepted on April 2, 2001

Gene expression measurements are a powerful tool in molecular biology, but when applied to heterogeneous samples containing more than one cellular type the results are difficult to interpret. We present here a new approach to this problem allowing to deduce the gene expression profile of the various cellular types contained in a set of samples directly from the measurements taken on the whole sample.

Contact: davenet{at}ulb.ac.be


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