Bioinformatics Vol. 18 no. 2 2002
Pages 337-338
© 2002 Oxford University Press
Applications Note |
Generating samples under a Wright–Fisher neutral model of genetic variation
Department of Ecology and Evolution, University of Chicago, 1101 E. 57th Street, Chicago, IL 60637, USA
Received on August 8, 2001
; revised on September 13, 2001
; accepted on September 13, 2001
Summary: A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright–Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models.
Availability: The source code for the program (in the language C) is available at http://home.uchicago.edu/~rhudson1/source/mksamples.html.
Contact: rr-hudson{at}uchicago.edu
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