Bioinformatics Vol. 18 no. 3 2002
Pages 434-439
© 2002 Oxford University Press
JenPep: a database of quantitative functional peptide data for immunology
Edward Jenner Institute for Vaccine Research, Compton, Berkshire RG0 7NN, UK
Received on August 9, 2001
; revised on October 2, 2001
; accepted on October 18, 2001
Motivation: The compilation of quantitative binding data underlies attempts to derive tools for the accurate prediction of epitopes in cellular immunology and is part of our concerted goal to develop practical computational vaccinology.
Results: JenPep is a family of relational databases supporting the growing community of immunoinformaticians. It contains quantitative data on peptide binding to Major Histocompatibility Complexes (MHCs) and to Transmembrane Peptide Transporter (TAP), as well as an annotated list of T-cell epitopes.
Availability: The database is available via the Internet. An HTML interface allowing searching of the database can be found at the following address: http://www.jenner.ac.uk/JenPep.
Contact: darren.flower{at}jenner.ac.uk
* To whom correspondence should be addressed.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  C. Lundegaard, O. Lund, C. Kesmir, S. Brunak, and M. Nielsen Modeling the adaptive immune system: predictions and simulations Bioinformatics, December 15, 2007; 23(24): 3265 - 3275. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Vider-Shalit, V. Fishbain, S. Raffaeli, and Y. Louzoun Phase-Dependent Immune Evasion of Herpesviruses J. Virol., September 1, 2007; 81(17): 9536 - 9545. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. Hiss, A. Bredenbeck, F. O. Losch, P. Wrede, P. Walden, and G. Schneider Design of MHC I stabilizing peptides by agent-based exploration of sequence space Protein Eng. Des. Sel., March 1, 2007; 20(3): 99 - 108. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. T. Chang, D. Ghosh, D. E. Kirschner, and J. J. Linderman Peptide length-based prediction of peptide-MHC class II binding Bioinformatics, November 15, 2006; 22(22): 2761 - 2767. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Zhu, K. Udaka, J. Sidney, A. Sette, K. F. Aoki-Kinoshita, and H. Mamitsuka Improving MHC binding peptide prediction by incorporating binding data of auxiliary MHC molecules Bioinformatics, July 1, 2006; 22(13): 1648 - 1655. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Demine and P. Walden Testing the Role of gp96 as Peptide Chaperone in Antigen Processing J. Biol. Chem., May 6, 2005; 280(18): 17573 - 17578. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. A. Reche, H. Zhang, J.-P. Glutting, and E. L. Reinherz EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology Bioinformatics, May 1, 2005; 21(9): 2140 - 2141. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. Doytchinova, S. Hemsley, and D. R. Flower Transporter Associated with Antigen Processing Preselection of Peptides Binding to the MHC: A Bioinformatic Evaluation J. Immunol., December 1, 2004; 173(11): 6813 - 6819. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. A. Doytchinova, V. A. Walshe, N. A. Jones, S. E. Gloster, P. Borrow, and D. R. Flower Coupling In Silico and In Vitro Analysis of Peptide-MHC Binding: A Bioinformatic Approach Enabling Prediction of Superbinding Peptides and Anchorless Epitopes J. Immunol., June 15, 2004; 172(12): 7495 - 7502. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Bhasin and G.P.S. Raghava Analysis and prediction of affinity of TAP binding peptides using cascade SVM Protein Sci., March 1, 2004; 13(3): 596 - 607. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Guan, I. A. Doytchinova, C. Zygouri, and D. R. Flower MHCPred: a server for quantitative prediction of peptide-MHC binding Nucleic Acids Res., July 1, 2003; 31(13): 3621 - 3624. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Guan, I. A. Doytchinova, and D. R. Flower HLA-A3 supermotif defined by quantitative structure-activity relationship analysis Protein Eng. Des. Sel., January 1, 2003; 16(1): 11 - 18. [Abstract] [Full Text] [PDF]
|
|