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Bioinformatics Vol. 18 no. 3 2002
Pages 492-493
© 2002 Oxford University Press
Applications Note |
GRIMM: genome rearrangements web server
Department of Computer Science and Engineering, University of California, San Diego, CA 92093-0114, USA
Received on September 14, 2001
; revised on October 24, 2001
; accepted on October 27, 2001
Summary: Genome Rearrangements In Man and Mouse (GRIMM) is a tool for analyzing rearrangements of gene orders in pairs of unichromosomal and multichromosomal genomes, with either signed or unsigned gene data. Although there are several programs for analyzing rearrangements in unichromosomal genomes, this is the first to analyze rearrangements in multichromosomal genomes. GRIMM also provides a new algorithm for analyzing comparative maps for which gene directions are unknown.
Availability: A web server, with instructions and sample data, is available at http://www-cse.ucsd.edu/groups/bioinformatics/GRIMM.
Contact: gptesler{at}ucsd.edu
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