Skip Navigation

This Article
Right arrow FREE Full Text (Print PDF) Freely available
Right arrow FREE Full Text (Screen PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (4)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Colbourn, C. J.
Right arrow Articles by Tompa, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Colbourn, C. J.
Right arrow Articles by Tompa, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Bioinformatics Vol. 18 no. 4 2002
Pages 529-535
© 2002 Oxford University Press

Construction of optimal quality control for oligo arrays

Charles J. Colbourn 1, Alan C. H. Ling 2 and Martin Tompa 3,*

1 Department of Computer Science and Engineering, Arizona State University, Tempe, AZ 85287-5406, USA
2 Department of Computer Science, University of Vermont, Burlington, VT 05405, USA
3 Department of Computer Science and Engineering, Box 352350, University of Washington, Seattle, WA 98195-2350, USA

Received on June 13, 2001 ; revised on November 2, 2001 ; accepted on November 7, 2001

Motivation: Oligo arrays are important experimental tools for the high throughput measurement of gene expression levels. During production of oligo arrays, it is important to identify any faulty manufacturing step.

Results: We describe a practical algorithm for the construction of optimal quality control designs that identify any faulty manufacturing step. The algorithm uses hillclimbing, a search technique from combinatorial optimization. We also present the results of using this algorithm on all practical quality control design sizes.

Availability: On request from the authors.

Contact: tompa{at}cs.washington.edu

* To whom correspondence should be addressed.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.