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Bioinformatics Vol. 18 no. 5 2002
Pages 761-762
© 2002 Oxford University Press

Applications Note

Gene structure identification with MyGV using cDNA evidence and protein homologs to improve ab initio predictions

Wei Zhu 1 and Volker Brendel 1,2

1 Department of Zoology and Genetics, Iowa State University, Ames, IA 50011, USA
2 Department of Statistics, Iowa State University, Ames, IA 50011, USA

Received on October 2, 2001 ; revised on December 4, 2001 ; accepted on December 7, 2001

Summary: MyGV is an application to visualize (potentially genome-scale) gene structure annotation and prediction. The output of any external gene prediction program can be easily converted to a generalized format for input into MyGV. The application displays all input simultaneously in graphical representation, with a toggle option for a text-based view. Zooming capabilities allow detailed comparisons for specific genome locations. The tool is particularly helpful for refinement of ab initio predicted gene structures by spliced alignment with cDNA or protein homologs.

Availability: The program was written in Java and is freely available to non-commercial users by electronic download from http://bioinformatics.iastate.edu/bioinformatics2go/MyGV.

Contact: vbrendel{at}iastate.edu


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