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Bioinformatics Vol. 18 no. 7 2002
Pages 1011-1012
© 2002 Oxford University Press

Applications Note

TangleSolve: topological analysis of site-specific recombination

Yuki Saka and Mariel Vázquez *

Mathematics Department, U.C. Berkeley, Berkeley, CA 94720-3840, USA

Received on November 29, 2001 ; revised on January 22, 2002 ; accepted on January 29, 2002

Summary: TangleSolve is a program for analysing site-specific recombination using the tangle model. The program offers an easy-to-use graphical user interface and a visualization tool. Biologists working in topological enzymology can use this program to compute and visualize site-specific recombination mechanisms that accommodate their experimental data. TangleSolve can also prove useful as a teaching aid for mathematical biology and computational molecular biology courses.

Availability: http://bio.math.berkeley.edu/TangleSolve/

Contact: mariel{at}math.berkeley.edu

* To whom correspondence should be addressed.


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