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Bioinformatics Vol. 18 no. 8 2002
Pages 1135-1136
© 2002 Oxford University Press


Applications Note

TFBS: Computational framework for transcription factor binding site analysis

Boris Lenhard * and Wyeth W. Wasserman

Bioinformatics Unit, Center for Genomics and Bioinformatics, Karolinska Institutet, Stockholm, Sweden

Received on December 20, 2001 ; revised on February 22, 2002 ; accepted on February 28, 2002

Motivation: TFBS is a set of integrated, object-oriented Perl modules for transcription factor binding site detection and analysis. It implements objects representing specificity profile matrices, binding sites and sets thereof, pattern generators, and pattern database interfaces. The modules are interoperable with the BioPerl open source system.

Availability and Supplementary Information: The module package with documentation and example scripts are available at http://forkhead.cgb.ki.se/TFBS/

Contact: Boris.Lenhard{at}cgb.ki.se

* To whom correspondence should be addressed.


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