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Bioinformatics Vol. 19 no. 1 2003
Pages 2-9
© 2003 Oxford University Press


Review

Wavelets in bioinformatics and computational biology: state of art and perspectives

Pietro Liò

Department of Zoology, University of Cambridge, Cambridge, UK
European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambs, UK

Received on October 17, 2002 ; revised on May 21, 2002 and July 7, 2002 ; accepted on July 7, 2002

Motivation: At a recent meeting{dagger}, the wavelet transform was depicted as a small child kicking back at its father, the Fourier transform. Wavelets are more efficient and faster than Fourier methods in capturing the essence of data. Nowadays there is a growing interest in using wavelets in the analysis of biological sequences and molecular biology-related signals.

Results: This review is intended to summarize the potential of state of the art wavelets, and in particular wavelet statistical methodology, in different areas of molecular biology: genome sequence, protein structure and microarray data analysis. I conclude by discussing the use of wavelets in modeling biological structures.

Contact: plio{at}hgmp.mrc.ac.uk

{dagger} XIX SMC 2001 ‘Wavelets in Statistics’, Vico Equense, Naples, I, 2–7 April 2001.


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