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Bioinformatics Vol. 19 no. 12 2003
Pages 1578-1579
© 2003 Oxford University Press


Applications Note

RankGene: identification of diagnostic genes based on expression data

Yang Su 1, T.M. Murali 1,*, Vladimir Pavlovic 2, Michael Schaffer 1 and Simon Kasif 1,3

1 Bioinformatics Program, Boston University, Boston, MA 02215
2 Department of Computer Science, Rutgers University Piscataway, NJ 08854
3 Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA

Received on September 5, 2002 ; revised on December 13, 2002 ; accepted on January 10, 2003

Summary: RankGene is a program for analyzing gene expression data and computing diagnostic genes based on their predictive power in distinguishing between different types of samples. The program integrates into one system a variety of popular ranking criteria, ranging from the traditional t-statistic to one-dimensional support vector machines. This flexibility makes RankGene a useful tool in gene expression analysis and feature selection.

Availability: http://genomics10.bu.edu/yangsu/rankgene

Contact: murali{at}bu.edu

* To whom correspondence should be addressed.


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