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Bioinformatics Vol. 19 no. 13 2003
Pages 1664-1671
© 2003 Oxford University Press

PRECIS: Protein reports engineered from concise information in SWISS-PROT

A.L. Mitchell 1,2,*, J.R. Reich 3 and T.K. Attwood 1,2

1 School of Biological Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, UK, 2 EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK and 3 Discovery Informatics, Basilea Pharmaceutica Ltd, PO Box 3255, CH-4002, Basel, Switzerland

Received on October 31, 2002 ; revised on February 25, 2003 ; accepted on March 5, 2003

Motivation: There have been several endeavours to address the problem of annotating sequence data computationally, but the task is non-trivial and few tools have emerged that gather useful information on a given sequence, or set of sequences, in a simple and convenient manner. As more genome projects bear fruit, the mass of uncharacterized sequence data accumulating in public repositories grows ever larger. There is thus a pressing need for tools to support the process of automatic analysis and annotation of newly determined sequences. With this in mind, we have developed PRECIS, which automatically creates protein reports from sets of SWISS-PROT entries, collating results into structured reports, detailing known biological and medical information, literature and database cross-references, and relevant keywords.

Availability: The software is accessible online at: http://www.bioinf.man.ac.uk/cgi-bin/dbbrowser/precis/blast_precis.cgi

Contact: mitchell{at}ebi.ac.uk

* To whom correspondence should be addressed.


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A. L. Mitchell, A. Divoli, J.-H. Kim, M. Hilario, I. Selimas, and T. K. Attwood
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