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Bioinformatics Vol. 19 no. 13 2003
Pages 1714-1715
© 2003 Oxford University Press


Applications Note

CGH-Plotter: MATLAB toolbox for CGH-data analysis

Reija Autio 1, Sampsa Hautaniemi 1,*, Päivikki Kauraniemi 3, Olli Yli-Harja 1, Jaakko Astola 1, Maija Wolf 2 and Anne Kallioniemi 3

1 Institute of Signal Processing, Tampere University of Technology, PO Box 553, 33101 Tampere, Finland, 2 Medical Biotechnology Group, VTT Technical Research Centre of Finland, PO Box 106, FIN-20521 Turku, Finland and 3 Laboratory of Cancer Genetics, Institute of Medical Technology, University of Tampere and Tampere University Hospital FIN-33520 Tampere, Finland

Received on November 8, 2002 ; revised on February 14, 2003 ; accepted on March 4, 2003

Summary: CGH-Plotter is a MATLAB toolbox with a graphical user interface for the analysis of comparative genomic hybridization (CGH) microarray data. CGH-Plotter provides a tool for rapid visualization of CGH-data according to the locations of the genes along the genome. In addition, the CGH-Plotter identifies regions of amplifications and deletions, using k-means clustering and dynamic programming. The application offers a convenient way to analyze CGH-data and can also be applied for the analysis of cDNA microarray expression data. CGH-Plotter toolbox is platform independent and requires MATLAB 6.1 or higher to operate.

Availability: http://sigwww.cs.tut.fi/TICSP/CGH-Plotter

Contact: sampsa.hautaniemi{at}tut.fi

* To whom correspondence should be addressed.


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