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Bioinformatics Vol. 19 no. 3 2003
Pages 433-434
© 2003 Oxford University Press

Applications Note

KnowledgeEditor: a new tool for interactive modeling and analyzing biological pathways based on microarray data

Tetsuro Toyoda * and Akihiko Konagaya

Bioinformatics Group, Genomic Sciences Center, RIKEN, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa, 230-0045, Japan

Received on August 21, 2002 ; revised on September 12, 2002 ; accepted on September 24, 2002

Summary: KnowledgeEditor is a graphical workbench for biological experts to model biomolecular network graphs. The modeled network data are represented by SRML, and can be published via the internet with the help of plug-in module ‘GSCope’. KnowledgeEditor helps us to model and analyze biological pathways based on microarray data. It is possible to analyze the drawn networks by simulating up–down regulatory cascade in molecular interactions.

Availability: KnowledgeEditor is available at http://gscope.gsc.riken.go.jp/

Contact: bioinfo{at}gsc.riken.go.jp

* To whom correspondence should be addressed.


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