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Bioinformatics Vol. 19 no. 3 2003
Pages 435-436
© 2003 Oxford University Press


Applications Note

Modeling biological systems using Dynetica—a simulator of dynamic networks

Lingchong You 1, Apirak Hoonlor 2 and John Yin 3,*

1 Division of Chemistry and Chemical Engineering, California Institute of Technology
2 Department of Computer Sciences
3 Department of Chemical Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI 53706, USA

Received on April 22, 2002 ; revised on September 18, 2002 ; accepted on October 21, 2002

Summary: We present Dynetica, a user-friendly simulator of dynamic networks for constructing, visualizing, and analyzing kinetic models of biological systems. In addition to generic reaction networks, Dynetica facilitates construction of models of genetic networks, where many reactions are gene expression and interactions among gene products. Further, it integrates the capability of conducting both deterministic and stochastic simulations.

Availability and supplementary information: Dynetica 1.0, example models, and the user's guide are available at http://www.its.caltech.edu/~you/Dynetica/Dynetica_page.htm

Contact: you{at}cheme.caltech.edu yin{at}engr.wisc.edu

* To whom correspondence should be addressed.


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