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Bioinformatics Vol. 19 no. 5 2003
Pages 651-652
© 2003 Oxford University Press


Applications Note

TIGR Gene Indices clustering tools (TGICL): a software system for fast clustering of large EST datasets

Geo Pertea 1,*, Xiaoqiu Huang 2, Feng Liang 1,3, Valentin Antonescu 1, Razvan Sultana 1, Svetlana Karamycheva 1, Yuandan Lee 1, Joseph White 1, Foo Cheung 1, Babak Parvizi 1, Jennifer Tsai 1 and John Quackenbush 1,*

1 The Institute for Genomic Research, Rockville, MD 20850 USA
2 Department of Computer Science, Iowa State University, Ames, IA 50011 USA
3 Current address Invitrogen Corporation, Carlsbad, CA 92008 USA

Received on July 10, 2002 ; revised on August 12, 2002 ; accepted on August 16, 2002

TGICL is a pipeline for analysis of large Expressed Sequence Tags (EST) and mRNA databases in which the sequences are first clustered based on pairwise sequence similarity, and then assembled by individual clusters (optionally with quality values) to produce longer, more complete consensus sequences. The system can run on multi-CPU architectures including SMP and PVM.

Availability: http://www.tigr.org/tdb/tgi/software/

Contact: johnq{at}tigr.org; johnq{at}tigr.org

* To whom correspondence should be addressed.


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