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Bioinformatics Vol. 19 no. 5 2003
Pages 653-654
© 2003 Oxford University Press

Applications Note

DigiNorthern, digital expression analysis of query genes based on ESTs

Jianxin Wang and Ping Liang *

Department of Cancer Genetics and the Biomathematics & Biostatistics Core Facility, Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263, USA

Received on September 3, 2002 ; revised on November 11, 2002 ; accepted on November 22, 2002

Summary: DigiNorthern (DN) is a web-based tool for virtually displaying expression profiles of query genes based on EST sequences. Two utilities are available: DN1 takes one query gene and quantitatively display its expression levels in tissues/organs that express the gene with comparison between normal and neoplastic status of each tissue; DN2 takes two sequences as query genes and compares their expression profiles side by side.

Availability: DN is currently available for analyses of human and mouse genes and is accessible at http://falcon.roswellpark.org/DN. Options for other species may become available in future depending on user’s request and EST data availability.

Contact: ping.liang{at}roswellpark.org

* To whom correspondence should be addressed.


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