Bioinformatics Vol. 19 no. 5 2003
Pages 655-656
© 2003 Oxford University Press
Applications Note |
Gene expression data preprocessing
Unidad de Bioinformática, Centro Nacional de Investigaciones Oncológicas (CNIO), Melchor Fernández Almagro, 3 28029 Madrid, Spain
Received on September 17, 2002
; revised on October 28, 2002
; accepted on November 4, 2002
Summary: We present an interactive web tool for preprocessing microarray gene expression data. It analyses the data, suggests the most appropriate transformations and proceeds with them after user agreement. The normal preprocessing steps include scale transformations, management of missing values, replicate handling, flat pattern filtering and pattern standardization and they are required before performing any pattern analysis. The processed data set can be sent to other pattern analysis tools.
Availability: The web interface is accessible through http://bioinfo.cnio.es/cgi-bin/tools/dnarray/preprocess
Contact: jdopazo{at}cnio.es
* To whom correspondence should be addressed.
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