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Bioinformatics Vol. 19 no. 5 2003
Pages 665-666
© 2003 Oxford University Press

Applications Note

MHCBN: a comprehensive database of MHC binding and non-binding peptides

Manoj Bhasin , Harpreet Singh and G. P. S. Raghava *

Institute of Microbial Technology, Chandigarh, India

Received on August 17, 2002 ; revised on October 7, 2002 ; accepted on November 18, 2002

Summary: MHCBN is a comprehensive database of Major Histocompatibility Complex (MHC) binding and non-binding peptides compiled from published literature and existing databases. The latest version of the database has 19 777 entries including 17 129 MHC binders and 2648 MHC non-binders for more than 400 MHC molecules. The database has sequence and structure data of (a) source proteins of peptides and (b) MHC molecules. MHCBN has a number of web tools that include: (i) mapping of peptide on query sequence; (ii) search on any field; (iii) creation of data sets; and (iv) online data submission. The database also provides hypertext links to major databases like SWISS-PROT, PDB, IMGT/HLA-DB, GenBank and PUBMED.

Availability: MHCBN is available at http://www.imtech.res.in/raghava/mhcbn/. It’s SRS version is available from http://srs.ebi.ac.uk/

Contact: raghava{at}imtech.res.in

Supplementary information: http://www.imtech.res.in/raghava/mhcbn/supl/

* To whom correspondence should be addressed.


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