Bioinformatics Vol. 19 no. 7 2003
Pages 889-890
© 2003 Oxford University Press
Applications Note |
R/qtl: QTL mapping in experimental crosses
aunak Sen 2,
1 Department of Biostatistics, Johns
Hopkins University, 615 N. Wolfe St, Baltimore, MD 21205, USA
2 The Jackson Laboratory, 600 Main St, Bar
Harbor, ME 04609, USA
Received on October 11, 2002
; revised on December 13, 2002
; accepted on December 20, 2002
Summary: R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by multiple methods, with the possible inclusion of covariates.
Availability: The package is freely available at http://www.biostat.jhsph.edu/~kbroman/qtl.
Contact: kbroman{at}jhsph.edu
* To whom correspondence should be addressed.
Present address:
Department of Epidemiology and Biostatistics,
University of California, San Francisco, CA 94143, USA.
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  L Backdahl, J P Guo, M Jagodic, K Becanovic, B Ding, T Olsson, and J C Lorentzen Definition of arthritis candidate risk genes by combining rat linkage-mapping results with human case-control association data Ann Rheum Dis, December 1, 2009; 68(12): 1925 - 1932. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Sa, O. Twu, K. Hayton, S. Reyes, M. P. Fay, P. Ringwald, and T. E. Wellems Inaugural Articles: Geographic patterns of Plasmodium falciparum drug resistance distinguished by differential responses to amodiaquine and chloroquine PNAS, November 10, 2009; 106(45): 18883 - 18889. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. C. Munger, D. L. Aylor, H. A. Syed, P. M. Magwene, D. W. Threadgill, and B. Capel Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal Genes & Dev., November 1, 2009; 23(21): 2521 - 2536. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. S. Kim and J. C. Fay A Combined-Cross Analysis Reveals Genes With Drug-Specific and Background-Dependent Effects on Drug Sensitivity in Saccharomyces cerevisiae Genetics, November 1, 2009; 183(3): 1141 - 1151. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Feng, M. E. Deerhake, R. Keating, J. Thaisz, L. Xu, S.-W. Tsaih, R. Smith, T. Ishige, F. Sugiyama, G. A. Churchill, et al. Genetic Analysis of Blood Pressure in 8 Mouse Intercross Populations Hypertension, October 1, 2009; 54(4): 802 - 809. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. S. Yang, M. H. Vitaterna, A. D. Laposky, K. Shimomura, and F. W. Turek Genetic analysis of daily physical activity using a mouse chromosome substitution strain Physiol Genomics, September 1, 2009; 39(1): 47 - 55. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. L. Nehrenberg, S. Wang, R. M. Hannon, T. Garland Jr, and D. Pomp QTL Underlying Voluntary Exercise in Mice: Interactions with the "Mini Muscle" Locus and Sex J. Hered., August 10, 2009; (2009) esp066v1. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Cox, C. L. Ackert-Bicknell, B. L. Dumont, Y. Ding, J. T. Bell, G. A. Brockmann, J. E. Wergedal, C. Bult, B. Paigen, J. Flint, et al. A New Standard Genetic Map for the Laboratory Mouse Genetics, August 1, 2009; 182(4): 1335 - 1344. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. R. Prows, A. V. Winterberg, W. J. Gibbons Jr., B. B. Burzynski, C. Liu, and T. G. Nick Reciprocal backcross mice confirm major loci linked to hyperoxic acute lung injury survival time Physiol Genomics, July 9, 2009; 38(2): 158 - 168. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Vogel, M. Nestler, F. Ruschendorf, M.-D. Block, S. Tischer, R. Kluge, A. Schurmann, H.-G. Joost, and S. Scherneck Characterization of Nob3, a major quantitative trait locus for obesity and hyperglycemia on mouse chromosome 1 Physiol Genomics, July 9, 2009; 38(2): 226 - 232. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. M. Cao, A. Thomas, Y. Wang, S. Tsai, K. Logronio, and J. A. Shizuru A chromosome 16 quantitative trait locus regulates allogeneic bone marrow engraftment in nonmyeloablated mice Blood, July 2, 2009; 114(1): 202 - 210. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Wang, Y. Zheng, P. M Nishina, and J. K Naggert A new mouse model of metabolic syndrome and associated complications J. Endocrinol., July 1, 2009; 202(1): 17 - 28. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Ishikawa Mapping an Overdominant Quantitative Trait Locus for Heterosis of Body Weight in Mice J. Hered., July 1, 2009; 100(4): 501 - 504. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Saless, S. J. Litscher, G. E. L. Franco, M. J. Houlihan, S. Sudhakaran, K. A. Raheem, T. K. O'Neil, R. Vanderby, P. Demant, and R. D. Blank Quantitative trait loci for biomechanical performance and femoral geometry in an intercross of recombinant congenic mice: restriction of the Bmd7 candidate interval FASEB J, July 1, 2009; 23(7): 2142 - 2154. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. H. Leiter, P. C. Reifsnyder, R. Wallace, R. Li, B. King, and G. C. Churchill NOD x 129.H2g7 Backcross Delineates 129S1/SvImJ-Derived Genomic Regions Modulating Type 1 Diabetes Development in Mice Diabetes, July 1, 2009; 58(7): 1700 - 1703. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Manichaikul and K. W. Broman Binary Trait Mapping in Experimental Crosses With Selective Genotyping Genetics, July 1, 2009; 182(3): 863 - 874. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. M. Cao, L. C. Lazzeroni, S. Tsai, W. W. Pang, A. Kao, N. J. Camp, A. Thomas, and J. A. Shizuru Identification of a Major Susceptibility Locus for Lethal Graft-versus-Host Disease in MHC-Matched Mice J. Immunol., July 1, 2009; 183(1): 462 - 469. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. L. Shaw and S. C. Lesnick Genomic linkage of male song and female acoustic preference QTL underlying a rapid species radiation PNAS, June 16, 2009; 106(24): 9737 - 9742. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Pan Network-based multiple locus linkage analysis of expression traits Bioinformatics, June 1, 2009; 25(11): 1390 - 1396. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H.-S. Jung and K. K. Niyogi Quantitative Genetic Analysis of Thermal Dissipation in Arabidopsis Plant Physiology, June 1, 2009; 150(2): 977 - 986. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. R. Farber, J. E. Aten, E. A. Farber, V. de Vera, R. Gularte, A. Islas-Trejo, P. Wen, S. Horvath, M. Lucero, A. J. Lusis, et al. Genetic dissection of a major mouse obesity QTL (Carfhg2): integration of gene expression and causality modeling Physiol Genomics, May 13, 2009; 37(3): 294 - 302. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Ni, A. Pujar, K. Youens-Clark, I. Yap, P. Jaiswal, I. Tecle, C.-W. Tung, L. Ren, W. Spooner, X. Wei, et al. Gramene QTL database: development, content and applications Database, May 12, 2009; 2009(0): bap005 - bap005. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. H. Wallis, K. Wang, L. Marandi, E. Hsieh, T. Ning, G. Y.C. Chao, J. Sarmiento, A. D. Paterson, and P. Poussier Type 1 Diabetes in the BB Rat: A Polygenic Disease Diabetes, April 1, 2009; 58(4): 1007 - 1017. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. J. Bennett, S. S. Wang, X. Wang, X. Wu, and A. J. Lusis Genetic Regulation of Atherosclerotic Plaque Size and Morphology in the Innominate Artery of Hyperlipidemic Mice Arterioscler Thromb Vasc Biol, March 1, 2009; 29(3): 348 - 355. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Pfalz, H. Vogel, and J. Kroymann The Gene Controlling the Indole Glucosinolate Modifier1 Quantitative Trait Locus Alters Indole Glucosinolate Structures and Aphid Resistance in Arabidopsis PLANT CELL, March 1, 2009; 21(3): 985 - 999. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Manichaikul, J. Y. Moon, S. Sen, B. S. Yandell, and K. W. Broman A Model Selection Approach for the Identification of Quantitative Trait Loci in Experimental Crosses, Allowing Epistasis Genetics, March 1, 2009; 181(3): 1077 - 1086. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Yi and S. Banerjee Hierarchical Generalized Linear Models for Multiple Quantitative Trait Locus Mapping Genetics, March 1, 2009; 181(3): 1101 - 1113. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Gatti, A. A. Shabalin, T.-C. Lam, F. A. Wright, I. Rusyn, and A. B. Nobel FastMap: Fast eQTL mapping in homozygous populations Bioinformatics, February 15, 2009; 25(4): 482 - 489. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. A. Brockmann, S.-W. Tsaih, C. Neuschl, G. A. Churchill, and R. Li Genetic factors contributing to obesity and body weight can act through mechanisms affecting muscle weight, fat weight, or both Physiol Genomics, January 8, 2009; 36(2): 114 - 126. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z. Su, X. Wang, S.-W. Tsaih, A. Zhang, A. Cox, S. Sheehan, and B. Paigen Genetic basis of HDL variation in 129/SvImJ and C57BL/6J mice: importance of testing candidate genes in targeted mutant mice J. Lipid Res., January 1, 2009; 50(1): 116 - 125. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Shao, L. C. Burrage, D. S. Sinasac, A. E. Hill, S. R. Ernest, W. O'Brien, H.-W. Courtland, K. J. Jepsen, A. Kirby, E. J. Kulbokas, et al. Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis PNAS, December 16, 2008; 105(50): 19910 - 19914. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Joehanes and J. C. Nelson QGene 4.0, an extensible Java QTL-analysis platform Bioinformatics, December 1, 2008; 24(23): 2788 - 2789. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Korstanje, J. Desai, G. Lazar, B. King, J. Rollins, M. Spurr, J. Joseph, S. Kadambi, Y. Li, A. Cherry, et al. Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects Physiol Genomics, November 12, 2008; 35(3): 296 - 304. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. E. Bauman, J. S. Sinsheimer, E. M. Sobel, and K. Lange Mixed Effects Models for Quantitative Trait Loci Mapping With Inbred Strains Genetics, November 1, 2008; 180(3): 1743 - 1761. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Chen, T. Tong, and H. Zhao Considering dependence among genes and markers for false discovery control in eQTL mapping Bioinformatics, September 15, 2008; 24(18): 2015 - 2022. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. O. Bergland, A. Genissel, S. V. Nuzhdin, and M. Tatar Quantitative Trait Loci Affecting Phenotypic Plasticity and the Allometric Relationship of Ovariole Number and Thorax Length in Drosophila melanogaster Genetics, September 1, 2008; 180(1): 567 - 582. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. K. Funk, T. J. Maxwell, M. Izumi, D. Edwin, F. Kreisel, T. J. Ley, J. M. Cheverud, and T. A. Graubert Quantitative trait loci associated with susceptibility to therapy-related acute murine promyelocytic leukemia in hCG-PML/RARA transgenic mice Blood, August 15, 2008; 112(4): 1434 - 1442. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. M. Hill, K. W. Broman, E. Stupka, W. C. Smith, D. Jiang, and A. Sidow The C. savignyi genetic map and its integration with the reference sequence facilitates insights into chordate genome evolution Genome Res., August 1, 2008; 18(8): 1369 - 1379. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. P. Boyle, J. P. J. Saeij, S. Y. Harada, J. W. Ajioka, and J. C. Boothroyd Expression Quantitative Trait Locus Mapping of Toxoplasma Genes Reveals Multiple Mechanisms for Strain-Specific Differences in Gene Expression Eukaryot. Cell, August 1, 2008; 7(8): 1403 - 1414. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Banerjee, B. S. Yandell, and N. Yi Bayesian Quantitative Trait Loci Mapping for Multiple Traits Genetics, August 1, 2008; 179(4): 2275 - 2289. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. G. Tordoff, H. Shao, L. K. Alarcon, R. F. Margolskee, B. Mosinger, A. A. Bachmanov, D. R. Reed, and S. McCaughey Involvement of T1R3 in calcium-magnesium taste Physiol Genomics, August 1, 2008; 34(3): 338 - 348. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. M. Nichols, A. F. Edo, P. A. Wheeler, and G. H. Thorgaard The Genetic Basis of Smoltification-Related Traits in Oncorhynchus mykiss Genetics, July 1, 2008; 179(3): 1559 - 1575. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Doorenbos, S.-W. Tsaih, S. Sheehan, N. Ishimori, G. Navis, G. Churchill, K. DiPetrillo, and R. Korstanje Quantitative Trait Loci for Urinary Albumin in Crosses Between C57BL/6J and A/J Inbred Mice in the Presence and Absence of Apoe Genetics, May 1, 2008; 179(1): 693 - 699. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. P. Kenney-Hunt, B. Wang, E. A. Norgard, G. Fawcett, D. Falk, L. S. Pletscher, J. P. Jarvis, C. Roseman, J. Wolf, and J. M. Cheverud Pleiotropic Patterns of Quantitative Trait Loci for 70 Murine Skeletal Traits Genetics, April 1, 2008; 178(4): 2275 - 2288. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. V. Serreze, C. M. Choisy-Rossi, A. E. Grier, T. M. Holl, H. D. Chapman, J. R. Gahagan, M. A. Osborne, W. Zhang, B. L. King, A. Brown, et al. Through Regulation of TCR Expression Levels, an Idd7 Region Gene(s) Interactively Contributes to the Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in Nonobese Diabetic Mice J. Immunol., March 1, 2008; 180(5): 3250 - 3259. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Yang, C. Hu, H. Hu, R. Yu, Z. Xia, X. Ye, and J. Zhu QTLNetwork: mapping and visualizing genetic architecture of complex traits in experimental populations Bioinformatics, March 1, 2008; 24(5): 721 - 723. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. A. Johnson, N. Aoyama, N. H. Friedell, S. Ikeda, and A. Ikeda Genetic Modification of the Schisis Phenotype in a Mouse Model of X-Linked Retinoschisis Genetics, March 1, 2008; 178(3): 1785 - 1794. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Bernichtein, E. Petretto, S. Jamieson, A. Goel, T. J. Aitman, J. M. Mangion, and I. T. Huhtaniemi Adrenal Gland Tumorigenesis after Gonadectomy in Mice Is a Complex Genetic Trait Driven by Epistatic Loci Endocrinology, February 1, 2008; 149(2): 651 - 661. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. R. Prows, A. P. Hafertepen, A. V. Winterberg, W. J. Gibbons Jr., S. C. Wesselkamper, J. B. Singer, A. E. Hill, J. H. Nadeau, and G. D. Leikauf Reciprocal Congenic Lines of Mice Capture the Aliq1 Effect on Acute Lung Injury Survival Time Am. J. Respir. Cell Mol. Biol., January 1, 2008; 38(1): 68 - 77. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. S. Kim and J. C. Fay Genetic variation in the cysteine biosynthesis pathway causes sensitivity to pharmacological compounds PNAS, December 4, 2007; 104(49): 19387 - 19391. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. Wang, D. Teske, A. Tess, R. Kohlhepp, Y. Choi, C. Kendziorski, and A. R. Moser Identification of Novel Modifier Loci of ApcMin Affecting Mammary Tumor Development Cancer Res., December 1, 2007; 67(23): 11226 - 11233. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Burgio, M. Szatanik, J.-L. Guenet, M.-R. Arnau, J.-J. Panthier, and X. Montagutelli Interspecific Recombinant Congenic Strains Between C57BL/6 and Mice of the Mus spretus Species: A Powerful Tool to Dissect Genetic Control of Complex Traits Genetics, December 1, 2007; 177(4): 2321 - 2333. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M.-F. Roy, N. Riendeau, C. Bedard, P. Helie, G. Min-Oo, K. Turcotte, P. Gros, F. Canonne-Hergaux, and D. Malo Pyruvate kinase deficiency confers susceptibility to Salmonella typhimurium infection in mice J. Exp. Med., November 26, 2007; 204(12): 2949 - 2961. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. K. Haston, M. Begin, G. Dorion, and S. M. Cory Distinct Loci Influence Radiation-Induced Alveolitis from Fibrosing Alveolitis in the Mouse Cancer Res., November 15, 2007; 67(22): 10796 - 10803. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Feuerer, W. Jiang, P. D. Holler, A. Satpathy, C. Campbell, M. Bogue, D. Mathis, and C. Benoist Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes PNAS, November 13, 2007; 104(46): 18181 - 18186. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. R. De Miglio, P. Virdis, D. F. Calvisi, D. Mele, M. R. Muroni, M. Frau, F. Pinna, M. L. Tomasi, M. M. Simile, R. M. Pascale, et al. Identification and chromosome mapping of loci predisposing to colorectal cancer that control Wnt/{beta}-catenin pathway and progression of early lesions in the rat Carcinogenesis, November 1, 2007; 28(11): 2367 - 2374. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Manichaikul, A. A. Palmer, S. Sen, and K. W. Broman Significance Thresholds for Quantitative Trait Locus Mapping Under Selective Genotyping Genetics, November 1, 2007; 177(3): 1963 - 1966. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. P. Boer, D. Wright, L. Feng, D. W. Podlich, L. Luo, M. Cooper, and F. A. van Eeuwijk A Mixed-Model Quantitative Trait Loci (QTL) Analysis for Multiple-Environment Trial Data Using Environmental Covariables for QTL-by-Environment Interactions, With an Example in Maize Genetics, November 1, 2007; 177(3): 1801 - 1813. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. H. Briggs, M. D. McMullen, B. S. Gaut, and J. Doebley Linkage Mapping of Domestication Loci in a Large Maize Teosinte Backcross Resource Genetics, November 1, 2007; 177(3): 1915 - 1928. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Llamas, S. Belanger, S. Picard, and C. F. Deschepper Cardiac mass and cardiomyocyte size are governed by different genetic loci on either autosomes or chromosome Y in recombinant inbred mice Physiol Genomics, October 19, 2007; 31(2): 176 - 182. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. E. Davidson, Q. Li, G. A. Churchill, L. R. Osborne, and H. E. McDermid Modifier locus for exencephaly in Cecr2 mutant mice is syntenic to the 10q25.3 region associated with neural tube defects in humans Physiol Genomics, October 19, 2007; 31(2): 244 - 251. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Chen and C. Kendziorski A Statistical Framework for Expression Quantitative Trait Loci Mapping Genetics, October 1, 2007; 177(2): 761 - 771. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. E. Kiernan, R. Li, N. L. Hawes, G. A. Churchill, and T. Gridley Genetic Background Modifies Inner Ear and Eye Phenotypes of Jag1 Heterozygous Mice Genetics, September 1, 2007; 177(1): 307 - 311. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. R. Prows, A. P. Hafertepen, A. V. Winterberg, W. J. Gibbons Jr., C. Liu, and T. G. Nick Genetic analysis of hyperoxic acute lung injury survival in reciprocal intercross mice Physiol Genomics, August 20, 2007; 30(3): 271 - 281. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. A. Cartwright, M. Troggio, R. Velasco, and A. Gutin Genetic Mapping in the Presence of Genotyping Errors Genetics, August 1, 2007; 176(4): 2521 - 2527. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Yi, D. Shriner, S. Banerjee, T. Mehta, D. Pomp, and B. S. Yandell An Efficient Bayesian Model Selection Approach for Interacting Quantitative Trait Loci Models With Many Effects Genetics, July 1, 2007; 176(3): 1865 - 1877. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Yi, S. Banerjee, D. Pomp, and B. S. Yandell Bayesian Mapping of Genomewide Interacting Quantitative Trait Loci for Ordinal Traits Genetics, July 1, 2007; 176(3): 1855 - 1864. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Taylor, W. Valdar, A. Kumar, J. Flint, and R. Mott Management, presentation and interpretation of genome scans using GSCANDB Bioinformatics, June 15, 2007; 23(12): 1545 - 1549. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. H. Wallis, K. Wang, D. Dabrowski, L. Marandi, T. Ning, E. Hsieh, A. D. Paterson, J. P. Mordes, E. P. Blankenhorn, and P. Poussier A Novel Susceptibility Locus on Rat Chromosome 8 Affects Spontaneous but Not Experimentally Induced Type 1 Diabetes Diabetes, June 1, 2007; 56(6): 1731 - 1736. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. J. Macdonald and A. D. Long Joint Estimates of Quantitative Trait Locus Effect and Frequency Using Synthetic Recombinant Populations of Drosophila melanogaster Genetics, June 1, 2007; 176(2): 1261 - 1281. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Jia and S. Xu Mapping Quantitative Trait Loci for Expression Abundance Genetics, May 1, 2007; 176(1): 611 - 623. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. D. Holler, T. Yamagata, W. Jiang, M. Feuerer, C. Benoist, and D. Mathis The same genomic region conditions clonal deletion and clonal deviation to the CD8{alpha}{alpha} and regulatory T cell lineages in NOD versus C57BL/6 mice PNAS, April 24, 2007; 104(17): 7187 - 7192. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Ahlqvist, R. Bockermann, and R. Holmdahl Fragmentation of Two Quantitative Trait Loci Controlling Collagen-Induced Arthritis Reveals a New Set of Interacting Subloci J. Immunol., March 1, 2007; 178(5): 3084 - 3090. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. S. Yandell, T. Mehta, S. Banerjee, D. Shriner, R. Venkataraman, J. Y. Moon, W. W. Neely, H. Wu, R. von Smith, and N. Yi R/qtlbim: QTL with Bayesian Interval Mapping in experimental crosses Bioinformatics, March 1, 2007; 23(5): 641 - 643. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Y. Ideraabdullah, K. Kim, D. Pomp, J. L. Moran, D. Beier, and F. P.-M. d. Villena Rescue of the Mouse DDK Syndrome by Parent-of-Origin-Dependent Modifiers Biol Reprod, February 1, 2007; 76(2): 286 - 293. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. M. Nichols, K. W. Broman, K. Sundin, J. M. Young, P. A. Wheeler, and G. H. Thorgaard Quantitative Trait Loci x Maternal Cytoplasmic Environment Interaction for Development Rate in Oncorhynchus mykiss Genetics, January 1, 2007; 175(1): 335 - 347. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. R. Farber and J. F. Medrano Fine Mapping Reveals Sex Bias in Quantitative Trait Loci Affecting Growth, Skeletal Size and Obesity-Related Traits on Mouse Chromosomes 2 and 11 Genetics, January 1, 2007; 175(1): 349 - 360. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Vitarius, E. Sehayek, and J. L. Breslow Identification of quantitative trait loci affecting body composition in a mouse intercross PNAS, December 26, 2006; 103(52): 19860 - 19865. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. H. Johansson, M. A. Taylor, M. Jagodic, K. Tus, J. D. Schatzle, E. K. Wakeland, and M. Bennett Mapping of Quantitative Trait Loci Determining NK Cell-Mediated Resistance to MHC Class I-Deficient Bone Marrow Grafts in Perforin-Deficient Mice J. Immunol., December 1, 2006; 177(11): 7923 - 7929. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. W. Broman, S. Sen, S. E. Owens, A. Manichaikul, E. M. Southard-Smith, and G. A. Churchill The X Chromosome in Quantitative Trait Locus Mapping Genetics, December 1, 2006; 174(4): 2151 - 2158. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. M. Hines, P. L. Hoffman, S. Bhave, L. Saba, A. Kaiser, L. Snell, I. Goncharov, L. LeGault, M. Dongier, B. Grant, et al. A Sex-Specific Role of Type VII Adenylyl Cyclase in Depression J. Neurosci., November 29, 2006; 26(48): 12609 - 12619. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. C. Solberg, A. E. Baum, N. Ahmadiyeh, K. Shimomura, R. Li, F. W. Turek, J. S. Takahashi, G. A. Churchill, and E. E. Redei Genetic analysis of the stress-responsive adrenocortical axis Physiol Genomics, November 21, 2006; 27(3): 362 - 369. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. Nathan, C. A. Hodges, P. J. Supelak, L. C. Burrage, J. H. Nadeau, and M. R. Palmert A Quantitative Trait Locus on Chromosome 6 Regulates the Onset of Puberty in Mice Endocrinology, November 1, 2006; 147(11): 5132 - 5138. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Granhall, H.-B. Park, H. Fakhrai-Rad, and H. Luthman High-Resolution Quantitative Trait Locus Analysis Reveals Multiple Diabetes Susceptibility Loci Mapped to Intervals <800 kb in the Species-Conserved Niddm1i of the GK Rat Genetics, November 1, 2006; 174(3): 1565 - 1572. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Z. Liu, K. Adamczyk, M. Manzanares-Dauleux, F. Eber, M.-O. Lucas, R. Delourme, A. M. Chevre, and E. Jenczewski Mapping PrBn and Other Quantitative Trait Loci Responsible for the Control of Homeologous Chromosome Pairing in Oilseed Rape (Brassica napus L.) Haploids Genetics, November 1, 2006; 174(3): 1583 - 1596. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Llamas, C. Lau, W. A. Cupples, M.-L. Rainville, E. Souzeau, and C. F. Deschepper Genetic Determinants of Systolic and Pulse Pressure in an Intercross Between Normotensive Inbred Rats Hypertension, November 1, 2006; 48(5): 921 - 926. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Kess, A.-K. B. Lindqvist, T. Peters, H. Wang, J. Zamek, R. Nischt, K. W. Broman, R. Blakytny, T. Krieg, R. Holmdahl, et al. Identification of Susceptibility Loci for Skin Disease in a Murine Psoriasis Model J. Immunol., October 1, 2006; 177(7): 4612 - 4619. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Rodo, L. A. Goncalves, J. Demengeot, A. Coutinho, and C. Penha-Goncalves MHC Class II Molecules Control Murine B Cell Responsiveness to Lipopolysaccharide Stimulation J. Immunol., October 1, 2006; 177(7): 4620 - 4626. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A.-K. B. Lindqvist, M. Johannesson, A. C. M. Johansson, K. S. Nandakumar, A. M. Blom, and R. Holmdahl Backcross and Partial Advanced Intercross Analysis of Nonobese Diabetic Gene-Mediated Effects on Collagen-Induced Arthritis Reveals an Interactive Effect by Two Major Loci J. Immunol., September 15, 2006; 177(6): 3952 - 3959. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Sehayek, L. R. Hagey, Y.-Y. Fung, E. M. Duncan, H. J. Yu, G. Eggertsen, I. Bjorkhem, A. F. Hofmann, and J. L. Breslow Two loci on chromosome 9 control bile acid composition: evidence that a strong candidate gene, Cyp8b1, is not the culprit J. Lipid Res., September 1, 2006; 47(9): 2020 - 2027. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Manichaikul, J. Dupuis, S. Sen, and K. W. Broman Poor Performance of Bootstrap Confidence Intervals for the Location of a Quantitative Trait Locus Genetics, September 1, 2006; 174(1): 481 - 489. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. H. Chadwick, L. M. Pertz, K. W. Broman, M. S. Bartolomei, and H. F. Willard Genetic Control of X Chromosome Inactivation in Mice: Definition of the Xce Candidate Interval Genetics, August 1, 2006; 173(4): 2103 - 2110. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Feenstra, I. M. Skovgaard, and K. W. Broman Mapping Quantitative Trait Loci by an Extension of the Haley-Knott Regression Method Using Estimating Equations Genetics, August 1, 2006; 173(4): 2269 - 2282. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Chen and J. D. Storey Relaxed Significance Criteria for Linkage Analysis Genetics, August 1, 2006; 173(4): 2371 - 2381. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. J. Armstrong, M. S. McPeek, and T. P. Speed Incorporating interference into linkage analysis for experimental crosses Biostat., July 1, 2006; 7(3): 374 - 386. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Ockinger, P. Serrano-Fernandez, S. Moller, S. M. Ibrahim, T. Olsson, and M. Jagodic Definition of a 1.06-Mb Region Linked to Neuroinflammation in Humans, Rats and Mice Genetics, July 1, 2006; 173(3): 1539 - 1545. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Liljander, M.-A. Sallstrom, S. Andersson, P. Wernhoff, A. Andersson, R. Holmdahl, and R. Mattsson Identification of Genetic Regions of Importance for Reproductive Performance in Female Mice Genetics, June 1, 2006; 173(2): 901 - 909. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. W. Burgess, T. J. Jucius, and S. L. Ackerman Motor Axon Guidance of the Mammalian Trochlear and Phrenic Nerves: Dependence on the Netrin Receptor Unc5c and Modifier Loci J. Neurosci., May 24, 2006; 26(21): 5756 - 5766. [Abstract] [Full Text] [PDF]
|
|