Bioinformatics Vol. 19 no. 7 2003
Pages 889-890
© 2003 Oxford University Press
Applications Note |
R/qtl: QTL mapping in experimental crosses
aunak Sen 2,
1 Department of Biostatistics, Johns
Hopkins University, 615 N. Wolfe St, Baltimore, MD 21205, USA
2 The Jackson Laboratory, 600 Main St, Bar
Harbor, ME 04609, USA
Received on October 11, 2002
; revised on December 13, 2002
; accepted on December 20, 2002
Summary: R/qtl is an extensible, interactive environment for mapping quantitative trait loci (QTLs) in experimental populations derived from inbred lines. It is implemented as an add-on package for the freely-available statistical software, R, and includes functions for estimating genetic maps, identifying genotyping errors, and performing single-QTL and two-dimensional, two-QTL genome scans by multiple methods, with the possible inclusion of covariates.
Availability: The package is freely available at http://www.biostat.jhsph.edu/~kbroman/qtl.
Contact: kbroman{at}jhsph.edu
* To whom correspondence should be addressed.
Present address:
Department of Epidemiology and Biostatistics,
University of California, San Francisco, CA 94143, USA.
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