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Bioinformatics Vol. 19 Suppl. 1 2003
Pages i313-i314
© 2003 Oxford University Press

Skew in CG content near the transcription start site in Arabidopsis thaliana

Tatiana Tatarinova , Vyacheslav Brover , Maxim Troukhan and Nickolai Alexandrov *

Ceres, Inc, 3007 Malibu Canyon Road, Malibu, CA, 90265, USA

Received on January 6, 2003 ; accepted on February 20, 2003

We have discovered a novel statistical feature of Arabidopsis thaliana genome that remarkably correlates with a position of transcription start site—CG skew peak. We hypothesize that the phenomenon can be explained by the higher mutability of unprotected cytosines.

Keywords: CG skew, promoter, transcription, mutation, full-length cDNA

Contact: nicka{at}ceres-inc.com

* To whom correspondence should be addressed.


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