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© IRL Press Limited

MATCH-UP/MATRIX: a microcomputer program designed to search for protein primary structure homology

A. Diehl , D. W. Rea and L. F. Hass *

Department of Biological Chemistry, The Milton S. Hershey Medical Center of The Pennsylvania State University Hershey, PA 17033, USA

*To whom reprint requests should be sent

MATCH-UP/MATRIX is a program designed to aid the investigator interested in determining primary protein structure. It is written in Applesoft BASIC for the Apple lle microcomputer. MATCH-UP will survey any set of proteinaceous materials for amino acid sequence homology; however, it is primarily intended to compare the structures of newly sequenced peptides with the established structure of a protein with suspected homology. Any peptide-to-protein alignment which shows a homology greater than or equal to the percentage specified by the user will result in output. MATRIX will compare the sequences of two proteins (peptides) in whatever alignment specified by the user and is intended to spot insertions and/or deletions between structures.

Received on December 2, 1985; accepted on March 10, 1986

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