Skip Navigation

This Article
Right arrow Full Text (Print PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Fielding, A. H.
Right arrow Articles by Smith, A. C.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Fielding, A. H.
Right arrow Articles by Smith, A. C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© IRL Press Limited

A rapid computer technique for analysing molecular interactions

Alan H. Fielding * and A. Christopher Smith

Department of Biological Sciences, Manchester Polytechnic Chester Street, Manchester M60 5GD, UK

*To whom reprint requests should be sent.

A rapid method for analysing enzyme — substrate interactions using a discriminant analysis program is described. This technque identifies the structural features of substrate molecules which are important in determining metabolic activity. Two model systems, nucleoside diphosphatase activity of Golgi membranes and the interaction of yeast hexokinase with a range of D-sugars, are used as illustrations of the technique. The conclusions from both models are consistent with those previously obtained from analytical techniques.

Received on January 21, 1986; accepted on April 1, 1986

Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.