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Bioinformatics 20(10) © Oxford University Press 2004; all rights reserved.

GCB Conference Paper

Conserved RNA secondary structures in viral genomes: a survey

I.L. Hofacker 1,*, P.F. Stadler 1,2 and R.R. Stocsits 1

1 Institut für Theoretische Chemie und Molekulare Strukturbiologie, Universität Wien, Währingerstraße 17, Vienna, A-1090, Austria and 2 Bioinformatik, Institut für Informatik, Universität Leipzig, Leipzig, D-04103, Germany

Received on October 12, 2003; accepted on February 3, 2004

Summary: The genomes of RNA viruses often carry conserved RNA structures that perform vital functions during the life cycle of the virus. Such structures can be detected using a combination of structure prediction and co-variation analysis. Here we present results from pilot studies on a variety of viral families performed during bioinformatics computer lab courses in past years.

Contact: ivo{at}tbi.univie.ac.at

* To whom correspondence should be addressed.


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