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Vol. 20 no. 2 2004, pages 268-270
Bioinformatics © Oxford University Press 2004; all rights reserved.

Applications Note

The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources

T. Crass 1,*, I. Antes 2, R. Basekow 3, P. Bork 4,5, C. Buning 6, M. Christensen 1, H. Claußen 6, C. Ebeling 7, P. Ernst 8, V. Gailus-Durner 9, K.-H. Glatting 8, R. Gohla 1, F. Gößling 11, K. Grote 9, K. Heidtke 3, A. Herrmann 5, S. O'Keeffe 9, O. Kießlich 3, S. Kolibal 6, J. O. Korbel 4,5, T. Lengauer 2, I. Liebich 1, M. van der Linden 8, H. Luz 12, K. Meissner 3, C. von Mering 4,5, H.-T. Mevissen 6, H.-W. Mewes 10, H. Michael 1, M. Mokrejs 10, T. Müller 12, H. Pospisil 5, M. Rarey 6, J. G. Reich 5, R. Schneider 9, D. Schomburg 7, S. Schulze-Kremer 3, K. Schwarzer 1, I. Sommer 2, S. Springstubbe 6, S. Suhai 8, G. Thoppae 10, M. Vingron 12, J. Warfsmann 10, T. Werner 9, D. Wetzler 7, E. Wingender 1 and R. Zimmer 6,13

1 Department of Bioinformatics, Medical Faculty, Georg August University Göttingen, Goldschmidtstrasse 1, 37077 Göttingen, Germany, 2 Max Planck Institute for Informatics, Computational Biology and Applied Algorithmics, Stuhlsatzenhausweg 85, 66123 Saarbrücken, Germany, 3 RZPD Deutsches Ressourcenzentrum für Genomforschung GmbH, Heubnerweg 6, 14059 Berlin, Germany, 4 European Molecular Biology Laboratory (EMBL), Structural and Computational Biology Programme, Meyerhofstraße 1, 69117 Heidelberg, Germany, 5 Department of Bioinformatics, Max Delbrück Center for Molecular Medicine (MDC), Robert-Roessle-Str. 10, 13125 Berlin, Germany, 6 Fraunhofer Institute for Algorithms and Scientific Computing (formerly GMD), Schloss Birlinghoven, 53754 Sankt Augustin, Germany, 7 Institute of Biochemistry, University of Cologne, Zuelpicher Straße 47, 50674 Cologne, Germany, 8 Department of Molecular Biophysics, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany, 9 Institute of Experimental Genetics, 10 Institute for Bioinformatics (MIPS-IBI), National Research Center for Environment and Health (GSF), Ingolstädter Landstraße 1, 85764 Neuherberg/Munich, Germany, 11 Genome Analysis Department, German Biotechnology Research Center (GBF), Mascheroder Weg 1, 38124 Braunschweig, Germany, 12 Bioinformatics Department, Max Planck Institute for Molecular Genetics, Ihnestraße 73, 14195 Berlin, Germany and 13 Institut für Informatik, Praktische Informatik und Bioinformatik, Ludwig Maximilian University Munich, Theresienstraße 39, 80333 Munich, Germany

Received on April 15, 2003 ; revised on July 24, 2003 ; accepted on July 31, 2003

Summary: The Helmholtz Network for Bioinformatics (HNB) is a joint venture of eleven German bioinformatics research groups that offers convenient access to numerous bioinformatics resources through a single web portal. The ‘Guided Solution Finder’ which is available through the HNB portal helps users to locate the appropriate resources to answer their queries by employing a detailed, tree-like questionnaire. Furthermore, automated complex tool cascades (‘tasks’), involving resources located on different servers, have been implemented, allowing users to perform comprehensive data analyses without the requirement of further manual intervention for data transfer and re-formatting. Currently, automated cascades for the analysis of regulatory DNA segments as well as for the prediction of protein functional properties are provided.

Availability: The HNB portal is available at http://www.hnbioinfo.de

Contact: torsten.crass{at}med.uni-goettingen.de

* To whom correspondence should be addressed.


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