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Bioinformatics Advance Access originally published online on January 22, 2004
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Bioinformatics 20(3) © Oxford University Press 2004; all rights reserved.

Applications Note

The Jalview Java alignment editor

Michele Clamp 1,2,4,*, James Cuff 1,2, Stephen M. Searle 1,2 and Geoffrey J. Barton 2,3,4

1 The Wellcome Trust Sanger Institute and 2 The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, CB10 1SA, UK, 3 School of Life Sciences, University of Dundee, Dow St, Dundee, DD1 5EH, UK and 4 The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7BN, UK

Received on April 16, 2003 ; revised on August 4, 2003 ; accepted on August 6, 2003
Advance Access Publication January 22, 2004

Summary: Multiple sequence alignment remains a crucial method for understanding the function of groups of related nucleic acid and protein sequences. However, it is known that automatic multiple sequence alignments can often be improved by manual editing. Therefore, tools are needed to view and edit multiple sequence alignments. Due to growth in the sequence databases, multiple sequence alignments can often be large and difficult to view efficiently. The Jalview Java alignment editor is presented here, which enables fast viewing and editing of large multiple sequence alignments.

Availability: The Jar file and source code for Jalview is freely available via the World Wide Web at http://www.jalview.org. A Jalview mailing list is also available by e-mailing majordomo{at}sanger.ac.uk with subscribe Jalview in the body of the mail.

Contact: michele{at}sanger.ac.uk

* To whom correspondence should be addressed.


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