Bioinformatics Advance Access originally published online on January 22, 2004
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Bioinformatics 20(4) © Oxford University Press 2004; all rights reserved.
Applications Note |
FatiGO: a web tool for finding significant associations of Gene Ontology terms with groups of genes
Bioinformatics Unit, Centro Nacional de Investigaciones Oncológicas (CNIO), Melchor Fernández Almagro 3, 28029 Madrid, Spain
Received on August 15, 2003
; revised on September 30, 2003
; accepted on October 1, 2003
Advance Access Publication January 22, 2004
Summary: We present a simple but powerful procedure to extract Gene Ontology (GO) terms that are significantly over- or under-represented in sets of genes within the context of a genome-scale experiment (DNA microarray, proteomics, etc.). Said procedure has been implemented as a web application, FatiGO, allowing for easy and interactive querying. FatiGO, which takes the multiple-testing nature of statistical contrast into account, currently includes GO associations for diverse organisms (human, mouse, fly, worm and yeast) and the TrEMBL/Swissprot GOAnnotations@EBI correspondences from the European Bioinformatics Institute.
Availability: http://fatigo.bioinfo.cnio.es
Contact: jdopazo{at}cnio.es
* To whom correspondence should be addressed.
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